PAEDIATRIC NEURORADIOLOGY

Neuroradiology

, Volume 42, Issue 10, pp 781-783

First online:

Wernicke's encephalopathy induced by total parenteral nutrition in patient with acute leukaemia: unusual involvement of caudate nuclei and cerebral cortex on MRI

  • P. D'AprileAffiliated withDivision of Neuroradiology, Department of Neurological Sciences, Policlinico, University of Bari, 70124 Bari, Italy Tel.: 39.0 80.5 47 85 07 Fax: 39.0 80.5 59 20 38
  • , A. TarantinoAffiliated withDivision of Neuroradiology, Department of Neurological Sciences, Policlinico, University of Bari, 70124 Bari, Italy Tel.: 39.0 80.5 47 85 07 Fax: 39.0 80.5 59 20 38
  • , N. SantoroAffiliated withInstitute of Paediatric Clinic I, Policlinico, University of Bari, Bari, Italy
  • , A. CarellaAffiliated withDivision of Neuroradiology, Department of Neurological Sciences, Policlinico, University of Bari, 70124 Bari, Italy Tel.: 39.0 80.5 47 85 07 Fax: 39.0 80.5 59 20 38

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Abstract

We report a 13-year-old girl with leukaemia and Wernicke's encephalopathy induced by total parenteral nutrition. MRI showed unusual bilateral lesions of the caudate nuclei and cerebral cortex, as well as typical lesions surrounding the third ventricle and aqueduct. After intravenous thiamine, the patient improved, and the abnormalities on MRI disappeared.

Key words Encephalopathy, Wernicke's Magnetic resonance imaging