Lesion load in unprotected carotid artery stenting
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- Grunwald, I.Q., Papanagiotou, P., Roth, C. et al. Neuroradiology (2009) 51: 313. doi:10.1007/s00234-008-0491-6
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The purpose of the study was to determine the incidence of new ischemic lesions found on diffusion-weighted MR imaging (DWI) in nonselected patients after unprotected carotid artery stent placement.
Materials and methods
We retrospectively reviewed a nonrandomized cohort of 197 patients presenting with carotid occlusive disease who underwent unprotected carotid artery stent placement between 2003 and 2006. Mean degree of stenosis was 86.94% ± 9.72. In all patients, DWI was obtained before and 24 h after stent placement. New lesions were evaluated according to size and location.
In 59 of 197 patients (29.9%), new ischemic lesions were found on DWI in the vessel dependent area. In 23 of 197 patients (11.7%), new ischemic lesions were found in the vessel independent area. Combined stroke/death rate was 3.63%.
In our series of unprotected carotid angioplasty with stent, we found new DWI lesions in 34% of the patients. Further studies should now show in how far protection devices can reduce these lesions.