, 50:701

Treatment of symptomatic high-grade intracranial stenoses with the balloon-expandable Pharos stent: initial experience


    • Department of NeuroradiologyUniversity of Frankfurt
  • J. Berkefeld
    • Department of NeuroradiologyUniversity of Frankfurt
  • M. Sitzer
    • Department of NeurologyKlinikum Herford
  • T. Neumann-Haefelin
    • Department of NeurologyUniversity of Frankfurt
  • R. du Mesnil de Rochemont
    • Department of NeuroradiologyUniversity of Frankfurt
Interventional Neuroradiology

DOI: 10.1007/s00234-008-0394-6

Cite this article as:
Kurre, W., Berkefeld, J., Sitzer, M. et al. Neuroradiology (2008) 50: 701. doi:10.1007/s00234-008-0394-6



We report our first clinical experience with a CE-marked flexible monorail balloon-expandable stent for treatment of high-grade intracranial stenoses.


Between April 2006 and November 2007 21 patients with symptomatic intracranial stenoses (>70%) were treated with the PHAROS stent. In seven patients, the procedure was performed during acute stroke intervention. Procedural success, clinical complication rates and mid-term follow-up data were prospectively recorded.


During a median follow-up period of 7.3 months one additional patient died of an unknown cause 3 months after the intervention. A patient with a significant residual stenosis presented with a new stroke after further progression of the residual stenosis. None of the successfully treated patients experienced ipsilateral stroke.


Recanalization of intracranial stenoses with the balloon-expandable Pharos stent is technically feasible. The periprocedural complication rate and mid-term follow-up results were in the range of previously reported case series. This pilot study was limited by the small sample size and severe morbidity of the included patients. Final evaluation of the efficacy of Pharos stent treatment demands further investigation.


Intracranial stenosisIntracranial stentingPharos stentBalloon-expandable stent

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© Springer-Verlag 2008