Neuroradiology

, Volume 50, Issue 2, pp 105–116

Clinical applications of susceptibility weighted MR imaging of the brain – a pictorial review

Authors

    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
  • Sivaraman Somasundaram
    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
  • Krishnamoorthy Thamburaj
    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
  • Chandrasekharan Kesavadas
    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
  • Arun Kumar Gupta
    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
  • Narendra K. Bodhey
    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
  • Tirur Raman Kapilamoorthy
    • Department of Imaging Sciences and Interventional RadiologySree Chitra Tirunal Institute for Medical Sciences and Technology
Diagnostic Neuroradiology

DOI: 10.1007/s00234-007-0316-z

Cite this article as:
Thomas, B., Somasundaram, S., Thamburaj, K. et al. Neuroradiology (2008) 50: 105. doi:10.1007/s00234-007-0316-z

Abstract

Introduction

Susceptibility-weighted imaging (SWI) is a novel magnetic resonance (MR) technique that exploits the magnetic susceptibility differences of various tissues, such as blood, iron and calcification. This pictorial review covers many clinical conditions illustrating its usefulness.

Methods

SWI consists of using both magnitude and phase images from a high-resolution, three-dimensional fully velocity-compensated gradient echo sequence. Phase mask is created from the MR phase images, and multiplying these with the magnitude images increase the conspicuity of the smaller veins and other sources of susceptibility effects, which is depicted using minimal intensity projection (minIP).

Results

The phase images are useful in differentiating between diamagnetic and paramagnetic susceptibility effects of calcium and blood, respectively. This unique MR sequence will help in detecting occult low flow vascular lesions, calcification and cerebral microbleed in various pathologic conditions and aids in characterizing tumors and degenerative diseases of the brain. This sequence also can be used to visualize normal brain structures with conspicuity.

Conclusion

Susceptibility-weighted imaging is useful in differentiating and characterizing diverse brain pathologies.

Keywords

BrainMagnetic resonance imagingSusceptibility weighted imaging

Copyright information

© Springer-Verlag 2007