Calcified Tissue International

, Volume 66, Issue 1, pp 1–4

The Relationship Between Phalangeal Bone Density and Vertebral Deformities

  • R. G. J. A.  Versluis
  • H.  Petri
  • F. J. F. E.  Vismans
  • C. M.  van de Ven
  • M. P.  Springer
  • S. E.  Papapoulos

DOI: 10.1007/s002230050001

Cite this article as:
Versluis, R., Petri, H., Vismans, F. et al. Calcif Tissue Int (2000) 66: 1. doi:10.1007/s002230050001

Abstract.

Radiographic absorptiometry (RA) of the phalanges is a convenient and reliable technique for measuring bone mineral density (BMD). It needs only a radiograph of the hand, which can be sent for evaluation to a central facility, whereas other techniques require specialized equipment. We assessed the relationship between RA measurements and the presence of vertebral deformities in a population-based cohort of postmenopausal women, and to compare the results with simultaneously obtained BMD of the hip by dual-energy X-ray absorptiometry (DXA). A total of 389 women aged 55–84 (mean age 67.2 years, SD 8.7) were randomly selected from a large general practice. RA, DXA of the hip, and vertebral deformities in the lateral spine X-rays by vertebral morphometry were assessed. Thirty-eight women (9.8%) had severe (grade II) vertebral deformities, and their BMD at the phalanges and femoral neck was significantly lower than that of women without severe vertebral deformities. Odds ratios for the presence of severe vertebral deformities of 1.5 (95% CI: 1.1–2.1) for RA and 1.3 (95% CI: 0.9–1.9) for DXA, together with similar receiver operating characteristics curves, were found using age-adjusted logistic regression. Phalangeal BMD is related to vertebral deformities at least as closely as BMD of the femoral neck BMD. RA may therefore help to evaluate fracture risk, especially if no DXA equipment is available.

Key words: Radiographic absorptiometry — Hand — Vertebral deformities — Bone mineral density.

Copyright information

© 2000 Springer-Verlag New York Inc.

Authors and Affiliations

  • R. G. J. A.  Versluis
    • 1
  • H.  Petri
    • 1
  • F. J. F. E.  Vismans
    • 2
  • C. M.  van de Ven
    • 3
  • M. P.  Springer
    • 1
  • S. E.  Papapoulos
    • 4
  1. 1.Department of General Practice, Leiden University Medical Centre, PO-box 2088, 2301 CB Leiden, The NetherlandsNL
  2. 2.Kennemer Gasthuis, Haarlem, The NetherlandsNL
  3. 3.Merck Sharp & Dohme, Haarlem, The NetherlandsNL
  4. 4.Department of Endocrinology and Metabolic Diseases, Leiden University Medical Centre, The NetherlandsNL