Calcified Tissue International

, Volume 86, Issue 3, pp 211–219

Influence of Lifestyle Factors on Quantitative Heel Ultrasound Measurements in Middle-Aged and Elderly Men

  • Stephen R. Pye
  • Vinodh Devakumar
  • Steven Boonen
  • Herman Borghs
  • Dirk Vanderschueren
  • Judith E. Adams
  • Kate A. Ward
  • Gyorgy Bartfai
  • Felipe F. Casanueva
  • Joseph D. Finn
  • Gianni Forti
  • Aleksander Giwercman
  • Thang S. Han
  • Ilpo T. Huhtaniemi
  • Krzysztof Kula
  • Michael E. J. Lean
  • Neil Pendleton
  • Margus Punab
  • Alan J. Silman
  • Frederick C. W. Wu
  • Terence W. O’Neill
  • EMAS Study Group
Article

DOI: 10.1007/s00223-009-9330-y

Cite this article as:
Pye, S.R., Devakumar, V., Boonen, S. et al. Calcif Tissue Int (2010) 86: 211. doi:10.1007/s00223-009-9330-y

Abstract

We examined the distribution of quantitative heel ultrasound (QUS) parameters in population samples of European men and looked at the influence of lifestyle factors on the occurrence of these parameters. Men aged between 40 and 79 years were recruited from eight European centers and invited to attend for an interviewer-assisted questionnaire, assessment of physical performance, and quantitative ultrasound (QUS) of the calcaneus (Hologic; Sahara). The relationships between QUS parameters and lifestyle variables were assessed using linear regression with adjustments for age, center, and weight. Three thousand two hundred fifty-eight men, mean age 60.0 years, were included in the analysis. A higher PASE score (upper vs. lower tertile) was associated with a higher BUA (β coefficient = 2.44 dB/Mhz), SOS (β = 6.83 m/s), and QUI (β = 3.87). Compared to those who were inactive, those who walked or cycled more than an hour per day had a higher BUA (β = 3.71 dB/Mhz), SOS (β = 6.97 m/s), and QUI (β = 4.50). A longer time to walk 50 ft was linked with a lower BUA (β = −0.62 dB/Mhz), SOS (β = −1.06 m/s), and QUI (β = −0.69). Smoking was associated with a reduction in BUA, SOS, and QUI. There was a U-shaped association with frequency of alcohol consumption. Modification of lifestyle, including increasing physical activity and stopping smoking, may help optimize bone strength and reduce the risk of fracture in middle-aged and elderly European men.

Keywords

EpidemiologyUltrasoundBone mineral densityRisk factorsExercise

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Stephen R. Pye
    • 1
  • Vinodh Devakumar
    • 1
  • Steven Boonen
    • 2
    • 3
  • Herman Borghs
    • 3
  • Dirk Vanderschueren
    • 3
    • 4
  • Judith E. Adams
    • 5
  • Kate A. Ward
    • 5
    • 6
  • Gyorgy Bartfai
    • 7
  • Felipe F. Casanueva
    • 8
    • 9
  • Joseph D. Finn
    • 1
  • Gianni Forti
    • 10
  • Aleksander Giwercman
    • 11
  • Thang S. Han
    • 12
  • Ilpo T. Huhtaniemi
    • 13
  • Krzysztof Kula
    • 14
  • Michael E. J. Lean
    • 15
  • Neil Pendleton
    • 16
  • Margus Punab
    • 17
  • Alan J. Silman
    • 1
  • Frederick C. W. Wu
    • 18
  • Terence W. O’Neill
    • 1
  • EMAS Study Group
  1. 1.ARC Epidemiology Unit, Manchester Academic Health Science CentreThe University of ManchesterManchesterUK
  2. 2.Leuven University Division of Geriatric MedicineKatholieke Universiteit LeuvenLeuvenBelgium
  3. 3.Leuven University Center for Metabolic Bone DiseasesKatholieke Universiteit LeuvenLeuvenBelgium
  4. 4.Department of Andrology and EndocrinologyKatholieke Universiteit LeuvenLeuvenBelgium
  5. 5.Clinical Radiology, Imaging Science and Biomedical Engineering, Manchester Academic Health Science CentreThe University of ManchesterManchesterUK
  6. 6.MRC Human Nutrition ResearchCambridgeUK
  7. 7.Department of Obstetrics, Gynaecology and AndrologyAlbert Szent-Gyorgy Medical UniversitySzegedHungary
  8. 8.Department of MedicineSantiago de Compostela University, Complejo Hospitalario Universitario de Santiago (CHUS)Santiago de CompostelaSpain
  9. 9.CIBER de Fisiopatología Obesidad y Nutricion (CB06/03), Instituto Salud Carlos IIISantiago de CompostelaSpain
  10. 10.Andrology Unit, Department of Clinical PhysiopathologyUniversity of FlorenceFlorenceItaly
  11. 11.Reproductive Medicine Centre, Malmö University HospitalUniversity of LundLundSweden
  12. 12.Department of EndocrinologyRoyal Free & University College Hospital Medical School, Royal Free HospitalLondonUK
  13. 13.Department of Reproductive BiologyImperial College LondonLondonUK
  14. 14.Department of Andrology and Reproductive EndocrinologyMedical University of LodzLodzPoland
  15. 15.Department of Human NutritionUniversity of GlasgowGlasgowScotland
  16. 16.Clinical Gerontology, Manchester Academic Health Science Centre, Hope HospitalThe University of ManchesterSalfordUK
  17. 17.Andrology UnitUnited Laboratories of Tartu University ClinicsTartuEstonia
  18. 18.Department of Endocrinology, Manchester Academic Health Science Centre, Manchester Royal InfirmaryThe University of ManchesterManchesterUK