Research Article

Experimental Brain Research

, Volume 215, Issue 2, pp 123-134

Effects of experimentally induced low back pain on the sit-to-stand movement and electroencephalographic contingent negative variation

  • Jesse V. JacobsAffiliated withDepartment of Rehabilitation and Movement Science, University of Vermont Email author 
  • , Chie YaguchiAffiliated withDepartment of Human Movement and Health, Kanazawa University
  • , Chizuru KaidaAffiliated withDepartment of Human Movement and Health, Kanazawa University
  • , Mariko IreiAffiliated withDepartment of Human Movement and Health, Kanazawa University
  • , Masami NakaAffiliated withDepartment of Human Movement and Health, Kanazawa University
  • , Sharon M. HenryAffiliated withDepartment of Rehabilitation and Movement Science, University of Vermont
  • , Katsuo FujiwaraAffiliated withDepartment of Human Movement and Health, Kanazawa University

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Abstract

It is becoming increasingly evident that people with chronic, recurrent low back pain (LBP) exhibit changes in cerebrocortical activity that associate with altered postural coordination, suggesting a need for a better understanding of how the experience of LBP alters postural coordination and cerebrocortical activity. To characterize changes in postural coordination and pre-movement cerebrocortical activity related to the experience of acutely induced LBP, 14 healthy participants with no history of LBP performed sit-to-stand movements in 3 sequential conditions: (1) without experimentally induced LBP; NoPain1, (2) with movement-associated LBP induced by electrocutaneous stimulation; Pain, and (3) again without induced LBP; NoPain2. The Pain condition elicited altered muscle activation and redistributed forces under the seat and feet prior to movement, decreased peak vertical force exerted under the feet during weight transfer, longer movement times, as well as decreased and earlier peak hip extension. Stepwise regression models demonstrated that electroencephalographic amplitudes of contingent negative variation during the Pain condition significantly correlated with the participants’ change in sit-to-stand measures between the NoPain1 and Pain conditions, as well as with the subsequent difference in sit-to-stand measures between the NoPain1 and NoPain2 conditions. The results, therefore, identify the contingent negative variation as a correlate for the extent of an individual’s LBP-related movement modifications and to the subsequent change in movement patterns from before to after the experience of acutely induced LBP, thereby providing a direction for future studies aimed to understand the neural mechanisms underlying the development of altered movement patterns with LBP.

Keywords

Contingent negative variation Low back pain Posture Sit-to-stand Electroencephalography