, Volume 227, Issue 1, pp 7-15
Date: 26 Jun 2007

Antihypertensive and antimicrobial bioactive peptides from milk proteins

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Introduction

Milk is an excellent source of well-balanced nutrients. Beyond this well-documented nutritive function, milk also exhibits a range of biological activities that influence the digestive function, metabolic responses to absorbed nutrients, growth and development of specific organs, and also disease resistance. These biological activities are mainly ascribed to the peptides and proteins, secreted into milk by the mammary gland. However, some of the biological activity of milk protein component is latent, and is released only upon proteolytic action. Such an activation of the latent biologically active protein component occurs usually during digestion of milk in the gut, and also during fermentation and processing. These bioactive peptides have been defined as specific protein fragments that have a positive impact on body functions or conditions and may ultimately influence health [1]. Upon oral administration, bioactive peptides, may affect the major body systems—namely, the c ...