Analytical and Bioanalytical Chemistry

, Volume 406, Issue 8, pp 2067–2099

Dispersive liquid–liquid microextraction in food analysis. A critical review

  • Pilar Viñas
  • Natalia Campillo
  • Ignacio López-García
  • Manuel Hernández-Córdoba
Review

DOI: 10.1007/s00216-013-7344-9

Cite this article as:
Viñas, P., Campillo, N., López-García, I. et al. Anal Bioanal Chem (2014) 406: 2067. doi:10.1007/s00216-013-7344-9
Part of the following topical collections:
  1. Microextraction Techniques

Abstract

An extensive critical evaluation of the application of dispersive liquid–liquid microextraction (DLLME) combined with chromatographic and atomic-spectroscopic methods for the determination of organic and inorganic compounds is presented. The review emphasizes the procedures used for the prior treatment of food samples, which are very different from the DLLME procedures generally proposed for water samples. The main contribution of this work in the field of DLLME reviews is its critical review of the abundant literature showing the increasing interest and practical advantages of using DLLME and closely related microextraction techniques for food analysis.

Keywords

Dispersive liquid–liquid microextractionSample pretreatmentMicroextraction techniquesFoodsReview

Abbreviations

DAD

Diode-array detection

DLLME

Dispersive liquid–liquid microextraction

ESI

Electrospray ionization

FLD

Fluorescence detection

GC

Gas chromatography

HF-LPME

Hollow-fiber-supported liquid-phase microextraction

IAC

Immunoaffinity column

I-DLLME

Inverted dispersive liquid–liquid microextraction

IL

Ionic liquid

LC

Liquid chromatography

LLE

Liquid–liquid extraction

LOD

Detection limit

LPME

Liquid-phase microextraction

MAE

Microwave-assisted extraction

MS

Mass spectrometry

MS/MS

Tandem mass spectrometry

QuEChERS

Quick, easy, cheap, effective, rugged, and safe

RP-DLLME

Reversed phase dispersive liquid–liquid microextraction

RP-LC

Reversed-phase liquid chromatography

SDME

Single-drop microextraction

SFE

Supercritical fluid extraction

SFO

Solidification of the floating organic drop

SPE

Solid-phase extraction

SPME

Solid-phase microextraction

UA-DLLME

Ultrasound-assisted dispersive liquid–liquid microextraction

UALLME

Ultrasound-assisted liquid–liquid microextraction

UASEME

Ultrasound-assisted surfactant-enhanced microextraction

UHPLC

Ultra-high-performance liquid chromatography

USAEME

Ultrasound-assisted emulsification microextraction

UV

Ultraviolet

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Pilar Viñas
    • 1
  • Natalia Campillo
    • 1
  • Ignacio López-García
    • 1
  • Manuel Hernández-Córdoba
    • 1
  1. 1.Department of Analytical ChemistryUniversity of Murcia, Regional Campus of International Excellence “Campus Mare Nostrum”MurciaSpain