, Volume 405, Issue 1, pp 21-26
Date: 30 Nov 2012

Defining a molecular portrait of physical fitness

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Introduction

To most individuals, the concept of fitness tends to conjure up mental images of physical attributes such as muscular definition or low body weight. However, while physical fitness (e.g., body weight, adiposity) is an important component of overall health, there are many “unseen” physiological and biological fitness alterations to the human body that have a far-reaching impact on health and wellness. Over the years, there have been many studies investigating the physiological implications, benefits, and consequences of physical fitness [1]. There are a number of important physiological adaptations, which occur with increasing aptitude in physical fitness. These adaptations include, but are not limited to, greater cardiorespiratory capacity/efficiency, denser bone structure, higher basal metabolic rates, and lower levels of adiposity [24]. Furthermore, each adaptation is linked to improved mortality and reduced risk of acute and chronic illnesses. However, though mostly ben ...