Development of silica-based stationary phases for high-performance liquid chromatography
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- Qiu, H., Liang, X., Sun, M. et al. Anal Bioanal Chem (2011) 399: 3307. doi:10.1007/s00216-010-4611-x
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Stationary phases are the basis of the development and application of high-performance liquid chromatography (HPLC). In this review we focused on the development of silica-based stationary phases, including the synthesis of silica gel and the application of silica in hydrophilic interaction chromatography (HILIC), reversed-phase liquid chromatography (RPLC), chiral separation chromatography, and ion chromatography. New stationary phases, advances in ionic liquid-modified silica, silica-based core-shell materials, and silica-based monolithic columns for HPLC are introduced separately.