Analytical and Bioanalytical Chemistry

, Volume 397, Issue 3, pp 1113–1135

Development and application of lateral flow test strip technology for detection of infectious agents and chemical contaminants: a review

Review

DOI: 10.1007/s00216-010-3661-4

Cite this article as:
Ngom, B., Guo, Y., Wang, X. et al. Anal Bioanal Chem (2010) 397: 1113. doi:10.1007/s00216-010-3661-4

Abstract

Recent progress in the laboratory has been a result of improvements in rapid analytical techniques. An update of the applications of lateral flow tests (also called immunochromatographic assay or test strip) is presented in this review manuscrit. We emphasized the description of this technology in the detection of a variety of biological agents and chemical contaminants (e.g. veterinary drugs, toxins and pesticides). It includes outstanding data, such as sample treatment, sensitivity, specificity, accuracy and reproducibility. Lateral flow tests provide advantages in simplicity and rapidity when compared to the conventional detection methods.

https://static-content.springer.com/image/art%3A10.1007%2Fs00216-010-3661-4/MediaObjects/216_2010_3661_Figa_HTML.gif

Overview of study using colored particles as label in lateral flow tests for the detection of pathogen agents and chemical contaminants. Data were obtained from a literature survey. The total number of published reports considered in this figure was seventy two

Keywords

Biological agentsChemical contaminantsLateral flow testsDetection methods

Abbreviations

AIV

Avian Inflenza Virus

CFU

Colony-forming unit

DNA

Deoxyribonucleic acid

ELISA

Enzyme-linked immunosorbant assay

GC-MS

Gas chromatography-mass spectrometry

HPLC

High performance Liquid Chromatography

ICA

Immunochromatographic assay

LFT

Lateral flow test strip

NALFIA

Nucleic acid lateral flow immunoassay

NALFT

Nucleic acid lateral flow test strip

RT-PCR

Reverse transcription-polymerase chain reaction

WHO

World Health Organisation

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  1. 1.State Key Laboratory of Agricultural Microbiology, College of Veterinary MedicineHuazhong Agricultural UniversityWuhanChina