Review

Analytical and Bioanalytical Chemistry

, Volume 395, Issue 4, pp 877-891

First online:

Antibiotics in food: Legislation and validation of analytical methodologies

  • R. CompanyóAffiliated withDepartament de Química Analítica, Facultat de Química, Universitat de Barcelona Email author 
  • , M. GranadosAffiliated withDepartament de Química Analítica, Facultat de Química, Universitat de Barcelona
  • , J. GuiterasAffiliated withDepartament de Química Analítica, Facultat de Química, Universitat de Barcelona
  • , M. D. PratAffiliated withDepartament de Química Analítica, Facultat de Química, Universitat de Barcelona

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

In this paper, European food safety legislation is presented, and special attention is devoted to monitoring residues of veterinary drugs in foodstuffs of animal origin. After a short review of the state of the art of analytical methodology for antibiotic residue analysis, the paper focuses on validation of analytical methods, with Decision 657/2002/EC as reference document. Finally, the main issues of the quality control of the analytical data, i.e. analysis of reference materials and participation in proficiency tests, are briefly addressed.

Keywords

Residues of antibiotics Food analysis Method validation Legislation Quality control Decision 2002/657/EC