Analytical and Bioanalytical Chemistry

, Volume 395, Issue 4, pp 877–891

Antibiotics in food: Legislation and validation of analytical methodologies

  • R. Companyó
  • M. Granados
  • J. Guiteras
  • M. D. Prat
Review

DOI: 10.1007/s00216-009-2969-4

Cite this article as:
Companyó, R., Granados, M., Guiteras, J. et al. Anal Bioanal Chem (2009) 395: 877. doi:10.1007/s00216-009-2969-4

Abstract

In this paper, European food safety legislation is presented, and special attention is devoted to monitoring residues of veterinary drugs in foodstuffs of animal origin. After a short review of the state of the art of analytical methodology for antibiotic residue analysis, the paper focuses on validation of analytical methods, with Decision 657/2002/EC as reference document. Finally, the main issues of the quality control of the analytical data, i.e. analysis of reference materials and participation in proficiency tests, are briefly addressed.

Keywords

Residues of antibioticsFood analysisMethod validationLegislationQuality controlDecision 2002/657/EC

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • R. Companyó
    • 1
  • M. Granados
    • 1
  • J. Guiteras
    • 1
  • M. D. Prat
    • 1
  1. 1.Departament de Química Analítica, Facultat de QuímicaUniversitat de BarcelonaBarcelonaSpain