Original Paper

Analytical and Bioanalytical Chemistry

, Volume 395, Issue 2, pp 411-419

First online:

Performance evaluation of a miniature ion mobility spectrometer drift cell for application in hand-held explosives detection ion mobility spectrometers

  • J. S. BabisAffiliated withUniversity of Arizona
  • , R. P. SperlineAffiliated withUniversity of Arizona
  • , A. K. KnightAffiliated withUniversity of Arizona
  • , D. A. JonesAffiliated withSandia National Laboratories
  • , C. A. GreshamAffiliated withSandia National Laboratories
  • , M. B. DentonAffiliated withUniversity of Arizona Email author 

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The implementation of hand-held ion mobility spectrometers (IMS) requires the development and evaluation of miniature drift cells providing high sensitivity while maintaining reasonable resolution. This manuscript describes the construction of a miniature IMS designed for such an application and its characterization by evaluation of the detection limits and resolution of the system with seven explosive compounds including trinitrotoluene (TNT), cyclotrimethylenetrinitramine (RDX), pentaerythritol tetranitrate (PETN), 2,4,6-trinitrophenyl-N-methylnitramine (Tetryl), nitroglycerin (NG), 2,4-dinitrotoluene (2,4 DNT), and 2,6-dinitrotoluene (2,6 DNT).


Miniature IMS Assembly


Miniature IMS Explosives Capacitive-transimpedance amplifier CTIA