Beyond blood sugar: the potential of NMR-based metabonomics for type 2 human diabetes, and the horse as a possible model
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- Hodavance, M.S., Ralston, S.L. & Pelczer, I. Anal Bioanal Chem (2007) 387: 533. doi:10.1007/s00216-006-0979-z
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Metabonomic analysis is a powerful tool for identifying and characterizing metabolic disorders, for example type 2 diabetes and the metabolic syndrome. Nuclear magnetic resonance (NMR) spectroscopy is an essential tool for such analysis, with special benefits. The review assesses the current status and potential of NMR-based metabonomics of type 2 diabetes. The horse is proposed as a possible model for studying this condition and disease. Some examples are shown of horse blood analyses by NMR.