Analytical and Bioanalytical Chemistry

, Volume 386, Issue 4, pp 1043-1047

First online:

Pressurized liquid extraction in environmental analysis

  • Michele M. SchantzAffiliated withAnalytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology Email author 

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A critical evaluation of recent literature utilizing pressurized liquid extraction (PLE) for environmental analysis is presented by compound class. Overall, the extraction efficiency of PLE, using the appropriate solvent, temperature and pressure for extraction, is similar to that of Soxhlet extraction. PLE has been used for some classes of compounds that are thermally labile (e.g., explosives) and may require acidic conditions for extraction (e.g., organometallic compounds). References to recent applications are presented emphasizing studies which utilize unspiked, natural matrices and studies that compare PLE to alternate extraction techniques.


Pressurized liquid extraction Pressurized fluid extraction Accelerated solvent extraction PLE PFE ASE