Analytical and Bioanalytical Chemistry

, Volume 372, Issue 1, pp 66–73

Developments in ion mobility spectrometry–mass spectrometry

  • D. Collins
  • M. Lee
Review

DOI: 10.1007/s00216-001-1195-5

Cite this article as:
Collins, D. & Lee, M. Anal Bioanal Chem (2002) 372: 66. doi:10.1007/s00216-001-1195-5

Abstract.

Ion mobility spectrometry (IMS) has been used for over 30 years as a sensitive detector of organic compounds. The following is a brief review of IMS and its principles with an emphasis on its usage when coupled to mass spectrometry. Since its inception, IMS has been interfaced with quadrupole, time-of-flight, and Fourier-transform ion cyclotron resonance mass spectrometry. These hybrid instruments have been employed for the analysis of a variety of target analytes, including biomolecules, explosives, chemical warfare degradation products, and illicit drugs.

Ion mobility spectrometry Mass spectrometry Gas-phase electrophoresis Plasma chromatography

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • D. Collins
    • 1
  • M. Lee
    • 2
  1. 1.Weber State University, Department of Criminal Justice, Ogden, Utah 84408–1206, USAUSA
  2. 2.Brigham Young University, Department of Chemistry and Biochemistry, Provo, Utah 84602–5700, USAUSA