Psychopharmacology

, Volume 216, Issue 3, pp 305–321

Delayed reward discounting and addictive behavior: a meta-analysis

  • James MacKillop
  • Michael T. Amlung
  • Lauren R. Few
  • Lara A. Ray
  • Lawrence H. Sweet
  • Marcus R. Munafò
Review

DOI: 10.1007/s00213-011-2229-0

Cite this article as:
MacKillop, J., Amlung, M.T., Few, L.R. et al. Psychopharmacology (2011) 216: 305. doi:10.1007/s00213-011-2229-0

Abstract

Rationale

Delayed reward discounting (DRD) is a behavioral economic index of impulsivity and numerous studies have examined DRD in relation to addictive behavior. To synthesize the findings across the literature, the current review is a meta-analysis of studies comparing DRD between criterion groups exhibiting addictive behavior and control groups.

Objectives

The meta-analysis sought to characterize the overall patterns of findings, systematic variability by sample and study type, and possible small study (publication) bias.

Methods

Literature reviews identified 310 candidate articles from which 46 studies reporting 64 comparisons were identified (total N = 56,013).

Results

From the total comparisons identified, a small magnitude effect was evident (d = .15; p < .00001) with very high heterogeneity of effect size. Based on systematic observed differences, large studies assessing DRD with a small number of self-report items were removed and an analysis of 57 comparisons (n = 3,329) using equivalent methods and exhibiting acceptable heterogeneity revealed a medium magnitude effect (d = .58; p < .00001). Further analyses revealed significantly larger effect sizes for studies using clinical samples (d = .61) compared with studies using nonclinical samples (d = .45). Indices of small study bias among the various comparisons suggested varying levels of influence by unpublished findings, ranging from minimal to moderate.

Conclusions

These results provide strong evidence of greater DRD in individuals exhibiting addictive behavior in general and particularly in individuals who meet criteria for an addictive disorder. Implications for the assessment of DRD and research priorities are discussed.

Keywords

Delay discounting Impulsivity Addiction Substance dependence Alcohol Tobacco Nicotine Stimulant Opiate Gambling Meta-analysis 

Supplementary material

213_2011_2229_MOESM1_ESM.pdf (105 kb)
ESM 1(PDF 105 kb)

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • James MacKillop
    • 1
    • 5
  • Michael T. Amlung
    • 1
  • Lauren R. Few
    • 1
  • Lara A. Ray
    • 2
  • Lawrence H. Sweet
    • 3
  • Marcus R. Munafò
    • 4
  1. 1.Department of PsychologyUniversity of GeorgiaAthensUSA
  2. 2.Department of PsychologyUniversity of CaliforniaLos AngelesUSA
  3. 3.Department of Psychiatry and Human BehaviorBrown UniversityProvidenceUSA
  4. 4.School of Experimental PsychologyUniversity of BristolBristolUK
  5. 5.Center for Alcohol and Addiction StudiesBrown UniversityProvidenceUSA

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