Psychopharmacology

, Volume 186, Issue 1, pp 32–40

Adaptive and maladaptive impulsivity, platelet monoamine oxidase (MAO) activity and risk-admitting in different types of risky drivers

  • Marika Paaver
  • Diva Eensoo
  • Aleksander Pulver
  • Jaanus Harro
Original Investigation

DOI: 10.1007/s00213-006-0325-3

Cite this article as:
Paaver, M., Eensoo, D., Pulver, A. et al. Psychopharmacology (2006) 186: 32. doi:10.1007/s00213-006-0325-3

Abstract

Rationale

Platelet monoamine oxidase (MAO) activity reflects serotonergic functioning associated with impulsive behaviour, but the significance of these associations to real-life impulsive behaviour in healthy subjects is not clear.

Objectives

The present study explores impulsivity and platelet MAO activity among people with driving violations.

Materials and methods

We compared facets of impulsivity and platelet MAO activity in 1,004 male drivers, out of whom 203 had been caught by the police driving drunk and 292 had been caught exceeding speed limits and committing other non-alcohol-related driving violations. Subjects with speeding and other non-alcohol-related violations were further divided according to their self-reported risk-admitting of exceeding speed limits.

Results

While drunk driving was associated only with maladaptive types of impulsivity, exceeding speed limits was associated with functional impulsivity and excitement seeking and, to a lesser degree, with dysfunctional impulsivity. Drunk drivers had lower platelet MAO activity. Risk-admitting high-risk drivers had higher platelet MAO activity, neuroticism-related impulsivity, dysfunctional impulsivity and excitement seeking compared to all other groups and higher functional impulsivity compared to controls. Risk-denying high-risk drivers had only higher functional impulsivity compared to controls.

Conclusions

This study demonstrates different expressions of functional and dysfunctional impulsivity in behaviour. While platelet MAO activity is lower in alcohol-related risky behaviour, non-alcohol-related self-acknowledged risky behaviour is related to higher platelet MAO activity. Thus, deviance towards lower as well as higher end of central serotonergic functioning may lead to impulsive behaviour. While self-reported impulsivity did not correlate with MAO activity, both MAO activity and impulsivity were related to risky behaviour.

Keywords

Impulsive behaviourFunctional impulsivityDysfunctional impulsivityDrunk drivingHigh-speed drivingCentral serotonergic activitySerotoninAlcoholismSmokingRisk perception

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Marika Paaver
    • 1
  • Diva Eensoo
    • 2
  • Aleksander Pulver
    • 3
  • Jaanus Harro
    • 1
  1. 1.Department of Psychology, Centre of Behavioural and Health SciencesUniversity of TartuTartuEstonia
  2. 2.Department of Public Health, Centre of Behavioural and Health SciencesUniversity of TartuTartuEstonia
  3. 3.Department of PsychologyUniversity of TallinnTallinnEstonia