Osteoporosis International

, Volume 11, Issue 5, pp 460–466

Deterioration in Quality of Life Following Hip Fracture: A Prospective Study

  • A. G. Randell
  • T. V. Nguyen
  • N. Bhalerao
  • S. L. Silverman
  • P. N. Sambrook
  • J. A. Eisman
Original Article

DOI: 10.1007/s001980070115

Cite this article as:
Randell, A., Nguyen, T., Bhalerao, N. et al. Osteoporos Int (2000) 11: 460. doi:10.1007/s001980070115

Abstract:

To examine longitudinal change in health- related quality of life (HRQoL) following hip fracture in elderly subjects, 32 patients with hip fractures and 29 sex-matched non-fracture control subjects (mean ± SD age 82 ± 8 and 86 ± 6 years respectively) were enrolled in a prospective, case–control study. Fracture subjects completed a generic questionnaire, Short Form 36 (SF-36), and a disease-targeted measure, the revised Osteoporosis Assessment Questionnaire (OPAQ2), on two separate occasions, within 1 week of fracture and 12–15 weeks after fracture. Controls completed both questionnaires on two occasions 12 weeks apart. SF-36 scores were significantly correlated with OPAQ2 in comparable domains of Physical Function (r= 0.76), General Health (r= 0.70) and Mental Health/Tension (r = 0.86). Control subjects had stable scores with the OPAQ2 and SF-36. At 3 months after fracture there was a significant reduction in HRQoL in the SF-36 domains Physical Function (–51%), Vitality (–24%) and Social Function (–26%) and in the OPAQ2 domains Physical Function (–20%), Social Activity (–49%) and General Health (–24%). Hip fracture patients thus had a lower baseline HRQoL and experienced a significant deterioration in HRQoL after hip fracture on both the SF-36 and OPAQ2. HRQoL should be part of a comprehensive assessment of the costs of osteoporosis including fracture-associated morbidity.

Key words:Hip fracture – Morbidity – Osteoporosis – Quality of life

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2000

Authors and Affiliations

  • A. G. Randell
    • 1
  • T. V. Nguyen
    • 1
  • N. Bhalerao
    • 1
  • S. L. Silverman
    • 2
  • P. N. Sambrook
    • 3
  • J. A. Eisman
    • 1
  1. 1.Bone and Mineral Research Program, Garvan Institute of Medical Research, St Vincent’s Hospital, Sydney, AustraliaAU
  2. 2.University of California Los Angeles, School of Medicine, Los Angeles, California, USAUS
  3. 3.Department of Rheumatology, University of Sydney, Royal North Shore Hospital, Sydney, AustraliaAU