Osteoporosis International

, Volume 11, Issue 8, pp 714–720

Femoral Bone Mineral Density, Neck-Shaft Angle and Mean Femoral Neck Width as Predictors of Hip Fracture in Men and Women

  • C. Gómez Alonso
  • M. Díaz Curiel
  • F. Hawkins Carranza
  • R. Pérez Cano
  • A. Díez Pérez
  • and the Multicenter Project for Research in Osteoporosis
Original Article

DOI: 10.1007/s001980070071

Cite this article as:
Gómez Alonso, C., Díaz Curiel, M., Hawkins Carranza, F. et al. Osteoporos Int (2000) 11: 714. doi:10.1007/s001980070071

Abstract:

The effect of femoral bone mineral density (BMD) and several parameters of femoral neck geometry (hip axis length, neck–shaft angle and mean femoral neck width) on hip fracture risk in a Spanish population was assessed in a cross-sectional study. All parameters were determined by dual-energy X-ray absorptiometry. There were 411 patients (116 men, 295 women; aged 60–90 years) with hip fractures in whom measurements were taken in the contralateral hip. Controls were 545 persons (235 men, 310 women; aged 60–90 years) who participated in a previous study on BMD in a healthy Spanish population. Femoral neck BMD was significantly lower, and neck–shaft angle and mean femoral neck width significantly higher, in fracture cases than in controls. The logistic regression analysis adjusted by age, height and weight showed that a decrease of 1 standard deviation (SD) in femoral neck BMD was associated with an odds ratio of hip fracture of 4.52 [95% confidence interval (CI) 2.93 to 6.96] in men and 4.45 (95% CI 3.11 to 6.36) in women; an increase of 1 SD in neck–shaft angle of 2.45 (95% CI 1.73 to 3.45) in men and 3.48 (95% CI 2.61 to 4.65) in women; and an increase of 1 SD in mean femoral neck width of 2.15 (95% CI 1.55 to 2.98) in men and 2.40 (95% CI 1.79 to 3.22) in women. The use of a combination of femoral BMD and geometric parameters of the femoral neck except for hip axis length may improve hip fracture risk prediction allowing a better therapeutic strategy for hip fracture prevention.

Key words: Accidental falls – Densitometry, X-ray – Femur neck – Fractures, prevention and control – Hip fractures – Osteoporosis, complications

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2000

Authors and Affiliations

  • C. Gómez Alonso
    • 1
  • M. Díaz Curiel
    • 2
  • F. Hawkins Carranza
    • 3
  • R. Pérez Cano
    • 4
  • A. Díez Pérez
  • and the Multicenter Project for Research in Osteoporosis
  1. 1.Servicio de Metabolismo Óseo y Mineral, Instituto Reivia Sofía de Investigacion, Hospital Central de Asturias, OviedoES
  2. 2.Unidad Metabólica, Fundación Jiménez Díaz, MadridES
  3. 3.Departamento de Endocrinología, Hospital Doce de Octubre, MadridES
  4. 4.Departamento de Medicina Interna, Hospital Virgen de la Macarena, Sevilla;ES
  5. 5.Servicio de Medicina Interna, Hospital del Mar, Barcelona, SpainES