Osteoporosis International

, Volume 23, Issue 4, pp 1351–1360

Lumbar spine bone mineral density in US adults: demographic patterns and relationship with femur neck skeletal status

  • A. C. Looker
  • L. J. MeltonIII
  • L. G. Borrud
  • J. A. Shepherd
Original Article

DOI: 10.1007/s00198-011-1693-z

Cite this article as:
Looker, A.C., Melton, L.J., Borrud, L.G. et al. Osteoporos Int (2012) 23: 1351. doi:10.1007/s00198-011-1693-z

Abstract

Summary

This analysis examines lumbar spine bone mineral density (BMD) of US adults from NHANES 2005–2008 by age, sex, and race/ethnicity. Prevalence of low spine BMD and agreement between the prevalence of low BMD at the spine and femur neck in older adults are also assessed.

Introduction

Lumbar spine BMD data from a representative sample of the US population have not been previously available.

Methods

We used data from the National Health and Nutrition Examination Survey 2005–2008 to examine demographic patterns in lumbar spine BMD among US adults age ≥20 years and the prevalence of low lumbar spine BMD in adults age ≥50 years. Agreement between the prevalence of low BMD at the femur neck and spine in older adults was also assessed. Dual-energy X-ray absorptiometry was used to measure lumbar spine and femur neck BMD. World Health Organization definitions were used to categorize skeletal status as normal, osteopenia, or osteoporosis.

Results

Compared to non-Hispanic whites, non-Hispanic blacks had higher and Mexican Americans had lower lumbar spine BMD. Lumbar spine BMD declined with age in women, but not in men. Approximately 4.7 million (10%) older US women and 1 million (3%) older men had lumbar spine osteoporosis in 2005–2008. Roughly one third of them differed in skeletal status at the spine and hip but most were normal at one site and osteopenic at the other. Only 3–10%, depending on sex, had osteoporosis at one skeletal site but not at the other skeletal site. Between 76% and 87% with discordant skeletal status had lumbar spine T-scores within 1 unit of the category threshold.

Conclusions

These findings suggest that measuring either the femur neck or the lumbar spine will correctly classify the majority of individuals who present for care as osteoporotic or not.

Keywords

Cross-sectional age patternsGender differencesLumbar spine bone mineral densityNHANESOsteoporosisRace/ethnic differences

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2011

Authors and Affiliations

  • A. C. Looker
    • 1
  • L. J. MeltonIII
    • 2
  • L. G. Borrud
    • 1
  • J. A. Shepherd
    • 3
  1. 1.National Center for Health Statistics, Centers for Disease Control and PreventionHyattsvilleUSA
  2. 2.Division of Epidemiology, College of MedicineMayo ClinicRochesterUSA
  3. 3.Department of RadiologyUniversity of California San FranciscoSan FranciscoUSA