, Volume 20, Issue 6, pp 1065-1075
Date: 02 Apr 2009

Diffraction techniques and vibrational spectroscopy opportunities to characterise bones

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Introduction

From a histological point of view, bones that allow body mobility and protection of internal organs consist not only of different organic and inorganic tissues but include vascular and nervous elements as well. Moreover, due to its ability to host different ions and cations, its mineral part represents an important reservoir, playing a key role in the metabolic activity of the organism. From a structural point of view, bones can be considered as a composite material displaying a hierarchical structure at different scales [1, 2]. At the nanometre scale, an organic part, i.e. collagen fibrils and an inorganic part, i.e. calcium phosphate nanocrystals [3, 4] are intimately mixed to assure particular mechanical properties.

A detailed understanding of the correlation between the mechanical properties and structural characteristic of bone has long been a prime concern of the medical community. Among the techniques often used to characterise such biological samples, diffraction tec ...

Data presented at the Third Meeting on Bone Quality, France, 24–25 June 2008: Bone Ultrastructure.