Osteoporosis International

, Volume 18, Issue 2, pp 245–249

Integrated anti-remodeling and anabolic therapy for the osteoporosis of Hajdu–Cheney syndrome

Case Report

DOI: 10.1007/s00198-006-0221-z

Cite this article as:
McKiernan, F.E. Osteoporos Int (2007) 18: 245. doi:10.1007/s00198-006-0221-z


Hajdu–Cheney syndrome (MIM 102500) is a rare skeletal dysplasia marked by severe generalized osteoporosis and focal bone loss (acro-osteolysis). Osteoporosis treatment outcome has been reported only once previously. Reported herein is the biochemical and densitometric response to integrated anti-remodeling and anabolic therapy in a woman with Hajdu–Cheney syndrome. Results suggest dissociation of bone formation from bone resorption resulting in dramatic increases in bone mineral density without clinical evidence of activated osteoporosis.


Bone mineral density Hajdu–Cheney syndrome Osteoporosis Remodeling 

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2006

Authors and Affiliations

  1. 1.Center for Bone DiseasesMarshfield ClinicMarshfieldUSA

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