Osteoporosis International

, Volume 16, Issue 12, pp 1703–1712

Does high-intensity resistance training maintain bone mass during moderate weight loss in older overweight adults with type 2 diabetes?

  • Robin M. Daly
  • David W. Dunstan
  • Neville Owen
  • Damien Jolley
  • Jonathan E. Shaw
  • Paul Z. Zimmet
Original Article

DOI: 10.1007/s00198-005-1906-4

Cite this article as:
Daly, R.M., Dunstan, D.W., Owen, N. et al. Osteoporos Int (2005) 16: 1703. doi:10.1007/s00198-005-1906-4

Abstract

The aim was to investigate whether the addition of supervised high intensity progressive resistance training to a moderate weight loss program (RT+WLoss) could maintain bone mineral density (BMD) and lean mass compared to moderate weight loss (WLoss) alone in older overweight adults with type 2 diabetes. We also investigated whether any benefits derived from a supervised RT program could be sustained through an additional home-based program. This was a 12-month trial in which 36 sedentary, overweight adults aged 60 to 80 years with type 2 diabetes were randomized to either a supervised gymnasium-based RT+WLoss or WLoss program for 6 months (phase 1). Thereafter, all participants completed an additional 6-month home-based training without further dietary modification (phase 2). Total body and regional BMD and bone mineral content (BMC), fat mass (FM) and lean mass (LM) were assessed by DXA every 6 months. Diet, muscle strength (1-RM) and serum total testosterone, estradiol, SHBG, insulin and IGF-1 were measured every 3 months. No between group differences were detected for changes in any of the hormonal parameters at any measurement point. In phase 1, after 6 months of gymnasium-based training, weight and FM decreased similarly in both groups (P<0.01), but LM tended to increase in the RT+WLoss (n=16) relative to the WLoss (n=13) group [net difference (95% CI), 1.8% (0.2, 3.5), P<0.05]. Total body BMD and BMC remained unchanged in the RT+WLoss group, but decreased by 0.9 and 1.5%, respectively, in the WLoss group (interaction, P<0.05). Similar, though non-significant, changes were detected at the femoral neck and lumbar spine (L2-L4). In phase 2, after a further 6 months of home-based training, weight and FM increased significantly in both the RT+WLoss (n=14) and WLoss (n=12) group, but there were no significant changes in LM or total body or regional BMD or BMC in either group from 6 to 12 months. These results indicate that in older, overweight adults with type 2 diabetes, dietary modification should be combined with progressive resistance training to optimize the effects on body composition without having a negative effect on bone health.

Keywords

Bone mineral densityResistance trainingType 2 diabetesWeight loss

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2005

Authors and Affiliations

  • Robin M. Daly
    • 1
  • David W. Dunstan
    • 2
  • Neville Owen
    • 3
  • Damien Jolley
    • 4
  • Jonathan E. Shaw
    • 2
  • Paul Z. Zimmet
    • 2
  1. 1.Center for Physical Activity and Nutrition Research, School of Exercise and Nutrition SciencesDeakin UniversityMelbourneAustralia
  2. 2.International Diabetes InstituteMelbourneAustralia
  3. 3.Cancer Prevention Research Center, School of Population HealthThe University of QueenslandBrisbaneAustralia
  4. 4.Monash Institute of Health Services ResearchMelbourneAustralia