Osteoporosis International

, Volume 15, Issue 11, pp 918–926

Establishing the compliance in elderly women for use of a low level mechanical stress device in a clinical osteoporosis study

  • Marian T. Hannan
  • Debbie M. Cheng
  • Emily Green
  • Cherie Swift
  • Clinton T. Rubin
  • Douglas P. Kiel
Original Article

DOI: 10.1007/s00198-004-1637-y

Cite this article as:
Hannan, M.T., Cheng, D.M., Green, E. et al. Osteoporos Int (2004) 15: 918. doi:10.1007/s00198-004-1637-y

Abstract

Non-pharmacologic approaches to prevent bone loss are well suited for elderly patients to avoid polypharmacy and medication side effects. One potential treatment is a vibrating platform that delivers low-level mechanical loading stimulating bone remodeling. However, compliance is a major concern with any daily treatment, and is unknown for an elderly group using this device. Thus we assessed compliance with standing 10 min/day on a vibrating platform device in elderly women, the target population for osteoporosis therapy. We also assessed satisfaction with daily use of the device. We conducted a randomized, placebo-controlled, double-blinded 6-month study for daily use of a 10-min vibrating platform treatment in elderly women who were residents of a Continuing Care Retirement community. Compliance for each subject was calculated as the number of days attended divided by the 182 days in the 6-month trial. The 24 elderly women (mean age 86, range 79–92 years) had 83% compliance (95% CI: 70.5, 94.5) for daily treatment over 6 months. Excluding three study drop-outs, the 21 women had 93% compliance (95% CI: 89.8, 95.6), with no difference in compliance between active and placebo treatment. Main reasons for missing treatment days over the 6 months were vacation (54% of missed days) and illness (29%). Three adverse events occurred; one (syncope) was possibly related to device use, whereas the other two were not related to device use. Among participants, 95% reported overall satisfaction with daily use of the vibrating platform, and 57% preferred the platform versus daily oral medications for prevention of bone loss. Elderly women showed high compliance, high satisfaction and few adverse experiences with a daily non-pharmacological treatment designed to inhibit bone loss. Larger randomized controlled trials should evaluate the long-term efficacy of vibrating platform devices for treatment of low bone mass and osteoporosis in elderly individuals.

Keywords

AgingBoneComplianceElderlyFeasibilityOsteoporosisRandomized controlled trial

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2004

Authors and Affiliations

  • Marian T. Hannan
    • 1
    • 5
  • Debbie M. Cheng
    • 2
  • Emily Green
    • 3
  • Cherie Swift
    • 3
  • Clinton T. Rubin
    • 4
  • Douglas P. Kiel
    • 1
  1. 1.Research & Training InstituteHebrew Rehabilitation Center for Aged and Harvard Medical School Division on AgingBostonUSA
  2. 2.Boston University School of Public HealthDepartment of BiostatisticsBostonUSA
  3. 3.Research & Training InstituteHebrew Rehabilitation Center for AgedBostonUSA
  4. 4.Department of Biomedical EngineeringState University of New York at Stony BrookStony BrookUSA
  5. 5.HRCA Research & Training InstituteBostonUSA