International Urogynecology Journal

, Volume 20, Issue 1, pp 53–60

General tissue characteristics of the lower urethral and vaginal walls in the domestic rabbit

  • Jorge Rodríguez-Antolín
  • Nicté Xelhuantzi
  • Mario García-Lorenzana
  • Estela Cuevas
  • Robyn Hudson
  • Margarita Martínez-Gómez
Original Article

DOI: 10.1007/s00192-008-0727-3

Cite this article as:
Rodríguez-Antolín, J., Xelhuantzi, N., García-Lorenzana, M. et al. Int Urogynecol J (2009) 20: 53. doi:10.1007/s00192-008-0727-3

Abstract

In European rabbits, the distal urethra (DU) opens into the anterior pelvic vagina forming a single canal by which females copulate, give birth, and urinate. We investigated whether the histological characteristics of the DU and the pelvic and perineal vagina are different. The DU and vagina of rabbits (Oryctolagus cuniculus) were cut and stained with hematoxylin–eosin and Masson’s trichrome (n = 3). Data were compared by using Friedman’s ANOVA for repeated measures. The walls of the DU and vagina are composed of mucosa, submucosa, smooth muscle, and an external layer. Differences in tissue characteristics of the mucosa, orientation of the smooth muscle fibers, components of the external layer (connective tissue, blood vessels, and striated musculature), and thickness of the tissue layers were found among regions. The lack of histological homogeneity along the urethra and vagina possibly reflects differences in the functions of each segment.

Keywords

Female rabbitMasson’s trichromeOryctolagus cuniculusUrethraUrogenital tractVagina

Abbreviations

DU

Distal urethra

V1

anterior pelvic vagina

V2

posterior pelvic vagina

V3

anterior perineal vagina

V4

posterior perineal vagina

Copyright information

© The International Urogynecological Association 2008

Authors and Affiliations

  • Jorge Rodríguez-Antolín
    • 1
  • Nicté Xelhuantzi
    • 1
  • Mario García-Lorenzana
    • 2
  • Estela Cuevas
    • 1
  • Robyn Hudson
    • 3
  • Margarita Martínez-Gómez
    • 4
  1. 1.Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMéxico
  2. 2.Departamento de Biología de la Reproducción, Área de NeurocienciasUniversidad Autónoma Metropolitana-IztapalapaDistrito FederalMéxico
  3. 3.Departamento de Fisiología y Biología Celular, Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoDistrito FederalMéxico
  4. 4.Unidad Periférica Tlaxcala, Departamento de Fisiología y Biología Celular, Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoTlaxcalaMéxico