The role of preoperative urodynamic testing in stress-continent women undergoing sacrocolpopexy: the Colpopexy and Urinary Reduction Efforts (CARE) randomized surgical trial

  • Anthony G. Visco
  • Linda Brubaker
  • Ingrid Nygaard
  • Holly E. Richter
  • Geoffrey Cundiff
  • Paul Fine
  • Halina Zyczynski
  • Morton B. Brown
  • Anne M. Weber
  • Pelvic Floor Disorders Network
Original Article

DOI: 10.1007/s00192-007-0498-2

Cite this article as:
Visco, A.G., Brubaker, L., Nygaard, I. et al. Int Urogynecol J (2008) 19: 607. doi:10.1007/s00192-007-0498-2

Abstract

The aim of this study is to describe results of reduction testing in stress-continent women undergoing sacrocolpopexy and to estimate whether stress leakage during urodynamic testing with prolapse reduction predicts postoperative stress incontinence. Three hundred twenty-two stress-continent women with stages II–IV prolapse underwent standardized urodynamics. Five prolapse reduction methods were tested: two at each site and both performed for each subject. Clinicians were masked to urodynamic results. At sacrocolpopexy, participants were randomized to Burch colposuspension or no Burch (control). P-values were computed by two-tailed Fisher’s exact test or t-test. Preoperatively, only 12 of 313 (3.7%) subjects demonstrated urodynamic stress incontinence (USI) without prolapse reduction. More women leaked after the second method than after the first (22% vs. 16%; p = 0.012). Preoperative detection of USI with prolapse reduction at 300ml was pessary, 6% (5 of 88); manual, 16% (19 of 122); forceps, 21% (21 of 98); swab, 20% (32 of 158); and speculum, 30% (35 of 118). Women who demonstrated preoperative USI during prolapse reduction were more likely to report postoperative stress incontinence, regardless of concomitant colposuspension (controls 58% vs. 38% (p = 0.04) and Burch 32% vs. 21% (p = 0.19)). In stress-continent women undergoing sacrocolpopexy, few women demonstrated USI without prolapse reduction. Detection rates of USI with prolapse reduction varied significantly by reduction method. Preoperative USI leakage during reduction testing is associated with a higher risk for postoperative stress incontinence at 3 months. Future research is warranted in this patient population to evaluate other treatment options to refine predictions and further reduce the risk of postoperative stress incontinence.

Keywords

Occult incontinence Urodynamics Prolapse reduction Sacrocolpopexy 

Copyright information

© International Urogynecology Journal 2007

Authors and Affiliations

  • Anthony G. Visco
    • 1
  • Linda Brubaker
    • 2
  • Ingrid Nygaard
    • 3
  • Holly E. Richter
    • 4
  • Geoffrey Cundiff
    • 5
  • Paul Fine
    • 6
  • Halina Zyczynski
    • 7
  • Morton B. Brown
    • 8
  • Anne M. Weber
    • 9
  • Pelvic Floor Disorders Network
  1. 1.Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and GynecologyDuke University Medical CenterDurhamUSA
  2. 2.Departments of Obstetrics and Gynecology and UrologyLoyola University Medical CenterMaywoodUSA
  3. 3.University of UtahSalt Lake CityUSA
  4. 4.Department of Obstetrics and GynecologyUniversity of Alabama at BirminghamBirminghamUSA
  5. 5.Providence Health CareVancouverCanada
  6. 6.Department of Obstetrics and GynecologyBaylor College of MedicineHoustonUSA
  7. 7.Department of Obstetrics and GynecologyUniversity of PittsburghPittsburghUSA
  8. 8.Department of BiostatisticsUniversity of MichiganAnn ArborUSA
  9. 9.National Institute of Child Health and Human DevelopmentRockvilleUSA

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