Knee Surgery, Sports Traumatology, Arthroscopy

, Volume 21, Issue 3, pp 636-640

First online:

No allergic reaction after TKA in a chrome-cobalt-nickel-sensitive patient: case report and review of the literature

  • Emmanuel ThienpontAffiliated withDepartment of Orthopaedic Surgery, Saint Luc University Hospital Email author 
  • , Yorick BergerAffiliated withDepartment of Orthopaedic Surgery, Saint Luc University Hospital

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Hypersensitivity to metallic implants remains relatively unpredictable and poorly understood. Although 20–25 % of total joint arthroplasty patients develop metal sensitivity, only a few highly susceptible persons (<1 %) exhibit symptoms. We present a case report of a fifty-two-year-old woman with a preoperatively documented metal allergy who underwent bilateral total knee arthroplasty using a titanium-niobium-coated implant on one side and a chrome-cobalt implant on the other side because of a logistics problem. At 2-year follow-up, no clinical symptoms of allergy or loosening of the implant were observed. Level of evidence IV.


Metal allergy Hypersensitivity Arthroplasty Implant loosening