Intensive Care Medicine

, Volume 24, Issue 12, pp 1335–1338

Prolonged severe hypercapnia complicating near fatal asthma in a 35-year-old woman

  • F. Adnet
  • P. Plaisance
  • S. W. Borron
  • A. Levy
  • D. Payen
BRIEF REPORT

DOI: 10.1007/s001340050772

Cite this article as:
Adnet, F., Plaisance, P., Borron, S. et al. Intensive Care Med (1998) 24: 1335. doi:10.1007/s001340050772

Abstract

Objective: We describe a patient with a prolonged and severe hypercapnia occurring during an episode of status asthmaticus induced by ophthalmic instillation of carteolol. Setting: Prehospital Emergency Medical Service and Pulmonary Intensive Care Unit in a university hospital. Patient: A 35-year-old female developed an acute asthma attack while at home, which required advanced life support. Intervention: On hospital admission, arterial blood gases revealed a PaCO2 of 208 mmHg. Hypercapnia persisted with a PaCO2 of more than 190 mmHg for 10 h, with pH always less than 7.00. The patient was finally discharged after 26 days without sequelae. Conclusion: This case illustrates the cerebral and cardiovascular tolerance of severe and prolonged hypercapnia associated with major acidosis.

Key words Near fatal asthma Mechanical ventilation Hypercapnia Respiratory acidosis 

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • F. Adnet
    • 1
  • P. Plaisance
    • 1
  • S. W. Borron
    • 2
  • A. Levy
    • 3
  • D. Payen
    • 1
  1. 1.SMUR Lariboisière, Department of Anesthesiology, CHU Lariboisière, University Paris VII, FranceFR
  2. 2.SAMU 93, Hopital Avicenne, 125 route de Stalingrad, F-93 009 Bobigny Cedex, France email: fadnet@compuserve.com Tel. + 33 1 48 96 44 00; Fax + 33 1 48 96 44 77FR
  3. 3.Respiratory Intensive Care Unit, Hopital Beaujon, University Paris VII, F-92 110 Clichy, FranceFR