Intensive Care Medicine

, Volume 36, Issue 2, pp 272–280

Prognostic factors in non-exertional heatstroke

  • Pierre Hausfater
  • Bruno Megarbane
  • Sandrine Dautheville
  • Anabella Patzak
  • Marc Andronikof
  • Aline Santin
  • Stéphanie André
  • Ludovic Korchia
  • Nabila Terbaoui
  • Gérald Kierzek
  • Benoît Doumenc
  • Christophe Leroy
  • Bruno Riou
Original

DOI: 10.1007/s00134-009-1694-y

Cite this article as:
Hausfater, P., Megarbane, B., Dautheville, S. et al. Intensive Care Med (2010) 36: 272. doi:10.1007/s00134-009-1694-y

Abstract

Purpose

To identify the prognostic factors associated with mortality in heat-related illness.

Methods

Multi-center observational cohort-study in 16 emergency departments (ED) belonging to the teaching hospital network of the Paris area. The cohort comprised all patients admitted to one of the EDs during the August 2003 heat wave in Paris and having a core temperature >38.5°C. Baseline clinical and biological data in ED, patient’s course and 1-year survival rate were recorded. Potential prognostic factors associated with death were assessed by Cox proportional-hazards analysis.

Results

A total of 1,456 patients were included. Mean age was 79 ± 19 years. Critically ill conditions were noted in 391 patients (27%), but only 72 (5%) were admitted into an intensive care unit. The survival rate was 57% at 1 year as compared to an expected 90% (P < 0.001). Nine independent prognostic factors were identified: previous treatment with diuretics, living in an institution, age >80 years, cardiac disease, cancer, core temperature >40°C, systolic arterial pressure <100 mmHg, Glasgow coma scale <12 and transportation to hospital by ambulance. We defined three risk groups: low, intermediate and high risk, with a 1-year survival rate of 85, 61 and 18%, respectively.

Conclusions

We observed a low survival rate and developed a risk score based on easily obtained variables that may be useful to clinicians managing casualties from future heat waves.

Keywords

HeatstrokeHeat waveRisk factorsElderly patientsMortalityTemperature

Copyright information

© Copyright jointly hold by Springer and ESICM 2009

Authors and Affiliations

  • Pierre Hausfater
    • 1
    • 13
  • Bruno Megarbane
    • 2
  • Sandrine Dautheville
    • 3
  • Anabella Patzak
    • 4
  • Marc Andronikof
    • 5
  • Aline Santin
    • 6
  • Stéphanie André
    • 7
  • Ludovic Korchia
    • 8
  • Nabila Terbaoui
    • 9
  • Gérald Kierzek
    • 10
  • Benoît Doumenc
    • 11
  • Christophe Leroy
    • 12
  • Bruno Riou
    • 1
  1. 1.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Pitié-Salpêtrière, Assistance-Publique Hôpitaux de ParisParisFrance
  2. 2.Critical Care DepartmentCentre Hospitalo-Universitaire (CHU) Lariboisière, Assistance-Publique Hôpitaux de ParisParisFrance
  3. 3.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Tenon, Assistance-Publique Hôpitaux de ParisParisFrance
  4. 4.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) George Pompidou, Assistance-Publique Hôpitaux de ParisParisFrance
  5. 5.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Antoine Béclère, Assistance-Publique Hôpitaux de ParisClamartFrance
  6. 6.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Henri Mondor, Assistance-Publique Hôpitaux de ParisCréteilFrance
  7. 7.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Cochin-St Vincent de Paul, Assistance-Publique Hôpitaux de ParisParisFrance
  8. 8.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Ambroise Paré, Assistance-Publique Hôpitaux de ParisBoulogneFrance
  9. 9.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Bichat-Claude Bernard, Assistance-Publique Hôpitaux de ParisParisFrance
  10. 10.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Hôtel Dieu, Assistance-Publique Hôpitaux de ParisParisFrance
  11. 11.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Bicêtre, Assistance-Publique Hôpitaux de ParisLe Kremlin BicêtreFrance
  12. 12.Emergency DepartmentCentre Hospitalo-Universitaire (CHU) Louis Mourier, Assistance-Publique Hôpitaux de ParisColombesFrance
  13. 13.Service d’Accueil des UrgencesGroupe Hospitalier Pitié-SalpêtrièreParisFrance