Pediatric Original

Intensive Care Medicine

, Volume 33, Issue 8, pp 1407-1413

First online:

Pediatric Index of Mortality 2 score in Italy: a multicenter, prospective, observational study

  • Andrea WolflerAffiliated withDepartment of Anesthesia and Intensive Care, Children’s Hospital Vittore Buzzi, Istituti Clinici di Perfezionamento Email author 
  • , Paolo SilvaniAffiliated withDepartment of Anesthesia and Intensive Care, Children’s Hospital Vittore Buzzi, Istituti Clinici di Perfezionamento
  • , Massimo MusiccoAffiliated withNational Research Council, Institute of Biomedical Technologies, IRCCS “Fondazione Santa Lucia”
  • , Ida SalvoAffiliated withDepartment of Anesthesia and Intensive Care, Children’s Hospital Vittore Buzzi, Istituti Clinici di Perfezionamento
  • , Italian Pediatric Sepsis Study (SISPe) GroupAffiliated withDepartment of Anesthesia and Intensive Care, Children’s Hospital Vittore Buzzi, Istituti Clinici di Perfezionamento

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Abstract

Objectives

To assess the performance of the Pediatric Index of Mortality (PIM) 2 score in Italian pediatric intensive care units (PICUs).

Design

Prospective, observational, multicenter, 1-year study.

Setting

Eighteen medical–surgical PICUs.

Patients

Consecutive patients (3266) aged 0–16 years admitted between 1 March 2004 and 28 February 2005.

Interventions

None.

Measurements and main results

To assess the performance of the PIM2 score, discrimination and calibration measures were applied to all children admitted to the 18 PICUs, in the entire population and in different groups divided for deciles of risk, age and admission diagnosis. There was good discrimination, with an area under the receiver operating characteristic (ROC) curve of 0.89 (95% CI 0.86–0.91) and good calibration of the scoring system [non-significant differences between observed and predicted deaths when the population was stratified according to deciles of risk (χ2 9.86; 8 df, p = 0.26) for the whole population].

Conclusions

The PIM2 score performed well in this sample of the Italian pediatric intensive care population. It may need to be reassessed in the injury and postoperative groups in larger studies.

Keywords

Pediatric intensive care unit Severity score Mortality Pediatric index of Mortality Children