, Volume 33, Issue 2, pp 214-229
Date: 13 Jan 2007

Year in review in Intensive Care Medicine, 2006. II. Infections and sepsis, haemodynamics, elderly, invasive and noninvasive mechanical ventilation, weaning, ARDS

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Respiratory infections

Acute exacerbations of chronic obstructive pulmonary disease

Cameron et al. [1] investigated the possible role of viruses in 107 episodes of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). They used modern diagnostic tests, including immunofluorescence assay and polymerase chain reaction, on nasopharyngeal aspirates. They identified infections in 64% of cases, with viruses as probable responsible pathogens in 43%: influenza type A (13%) and rhinovirus (8%) were the most common organisms. Bacteria were found in 23% of cases, with Haemophilus influenzae as the most common pathogen (11%). The authors failed to find significant differences in clinical characteristics and outcome between virus-infected and noninfected patients. In his related editorial, Luyt [2] comments more generally on virus in intensive care unit (ICU) patients, emphasizing (1) the questionable relationship between viral diseases and outcome, (2) the doubtful reliability of mo ...

This review summarizes all articles published in Intensive Care Medicine in 2006, grouped by specific topic.