Intensive Care Medicine

, Volume 31, Issue 8, pp 1029–1041

Inhaled nitric oxide therapy in adults: European expert recommendations

  • Peter Germann
  • Antonio Braschi
  • Giorgio Della Rocca
  • Anh Tuan Dinh-Xuan
  • Konrad Falke
  • Claes Frostell
  • Lars E. Gustafsson
  • Philippe Hervé
  • Philippe Jolliet
  • Udo Kaisers
  • Hector Litvan
  • Duncan J. Macrae
  • Marco Maggiorini
  • Nandor Marczin
  • Bernd Mueller
  • Didier Payen
  • Marco Ranucci
  • Dietmar Schranz
  • Rainer Zimmermann
  • Roman Ullrich
Special Article

DOI: 10.1007/s00134-005-2675-4

Cite this article as:
Germann, P., Braschi, A., Della Rocca, G. et al. Intensive Care Med (2005) 31: 1029. doi:10.1007/s00134-005-2675-4

Abstract

Background

Inhaled nitric oxide (iNO) has been used for treatment of acute respiratory failure and pulmonary hypertension since 1991 in adult patients in the perioperative setting and in critical care.

Methods

This contribution assesses evidence for the use of iNO in this population as presented to a expert group jointly organised by the European Society of Intensive Care Medicine and the European Association of Cardiothoracic Anaesthesiologists.

Conclusions

Expert recommendations on the use of iNO in adults were agreed on following presentation of the evidence at the expert meeting held in June 2004.

Keywords

Inhaled nitric oxidePulmonary hypertensionAcute respiratory distress syndromeAcute lung injuryCardiac surgeryLung transplantation

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Peter Germann
    • 1
  • Antonio Braschi
    • 2
  • Giorgio Della Rocca
    • 3
  • Anh Tuan Dinh-Xuan
    • 4
  • Konrad Falke
    • 5
  • Claes Frostell
    • 6
  • Lars E. Gustafsson
    • 7
  • Philippe Hervé
    • 8
  • Philippe Jolliet
    • 9
  • Udo Kaisers
    • 10
  • Hector Litvan
    • 11
  • Duncan J. Macrae
    • 12
  • Marco Maggiorini
    • 13
  • Nandor Marczin
    • 14
  • Bernd Mueller
    • 15
  • Didier Payen
    • 16
  • Marco Ranucci
    • 17
  • Dietmar Schranz
    • 18
  • Rainer Zimmermann
    • 18
  • Roman Ullrich
    • 1
  1. 1.Department of Anaesthesiology and General Intensive CareMedical University of ViennaViennaAustria
  2. 2.Department of Anaesthesia and Intensive CareUniversity of Pavia, IRCCS Policlinico S. MatteoPaviaItaly
  3. 3.Policlinico Universita UdineUdineItaly
  4. 4.Service de Physiologie-Explorations FonctionnellesHôpital CochinParis cedex 14France
  5. 5.Department of Anaesthesiology and Intensive Care Medicine, Charité Campus Virchow KlinikumUniversity Medical CenterBerlinGermany
  6. 6.Department of Anaesthesia and Intensive CareKarolinska Institutet, Danderyd HospitalDanderydSweden
  7. 7.Physiology and Pharmacology at Berzelius LabKarolinska InstitutetStockholmSweden
  8. 8.Service d’Explorations FonctionnellesCentre Chirurgical Marie LannelongueOrsayFrance
  9. 9.Division of Medical Intensive CareUniversity Hospital of GenevaGeneva 14Switzerland
  10. 10.Department of Anaesthesiology and Intensive Care Medicine, Charité Campus Virchow KlinikumUniversity Medical CenterBerlinGermany
  11. 11.Cardiac Anestesia and Postoperative Intensive Care UnitHospital Santa Creu i Sant PauBarcelonaSpain
  12. 12.Paediatric Intensive CareRoyal Brompton HospitalLondonUK
  13. 13.Intensive Care Unit, Department of Internal MedicineUniversitätsspitalZurichSwitzerland
  14. 14.Heart Science CentreHarefield HospitalHarefieldUK
  15. 15.Laboratory of Respiratory Cell Biology, Division of PneumologyPhilipps UniversityMarburgGermany
  16. 16.Département d’Anesthésie-Réanimation ChirurgicaleHôpital LariboisièreParis cedex 10France
  17. 17.Department of Cardiothoracic Anaesthesia and Intensive CareIstituto Policlinico S. DonatoS. Donato MilaneseItaly
  18. 18.Abteilung KinderkardiologieUniv.-Kinderklinik GiessenGiessenGermany