Intensive Care Medicine

, Volume 30, Issue 3, pp 437–443

Body mass index

An additional prognostic factor in ICU patients
  • Maité Garrouste-Orgeas
  • Gilles Troché
  • Elie Azoulay
  • Antoine Caubel
  • Arnaud de Lassence
  • Christine Cheval
  • Laurent Montesino
  • Marie Thuong
  • François Vincent
  • Yves Cohen
  • Jean-François Timsit
Original

DOI: 10.1007/s00134-003-2095-2

Cite this article as:
Garrouste-Orgeas, M., Troché, G., Azoulay, E. et al. Intensive Care Med (2004) 30: 437. doi:10.1007/s00134-003-2095-2

Abstract

Objective

To examine the association between body mass index (BMI) and mortality in adult intensive care unit (ICU) patients.

Design

A prospective multi-center study.

Interventions

None.

Methods

A cohort study (yielding the OUTCOMEREA database) was conducted over 2 years in 6 medical-surgical ICUs. In each participating ICU, the following were collected daily: demographic information, admission height and weight, comorbidities, severity scores (SAPS II, LOD, and SOFA), ICU and hospital lengths of stay, and ICU and hospital mortality rates.

Results

A total of 1,698 patients were examined and divided into 4 groups based on BMI: <18.5, 18.5–24.9, 25–29.9, and >30 kg/m2. These groups differed significantly for age, gender, admission category (medical, scheduled surgery, unscheduled surgery), ICU and hospital lengths of stay, and comorbidities. Severity at admission and within the first 2 days was similar in the 4 groups, except for the SOFA score. Overall hospital mortality was 31.3% (532 out of 1,698 patients). By multivariate analysis, a BMI below 18.5 kg/m2 was independently associated with increased mortality (odds ratio 1.63; 95% confidence intervals 1.11–2.39). None of the other BMI categories were associated with higher mortality and even a BMI>30 kg/m2 was protective of mortality (odds ratio 0.60, 95% confidence intervals 0.40–0.88).

Conclusions

A low BMI was independently associated with higher mortality and a high BMI with lower mortality in this large cohort of critically ill patients. Since BMI is absent from currently available scoring systems, further studies are needed to determine whether adding BMI would improve the effectiveness of scores in predicting mortality.

Keywords

Intensive care unitBody mass indexEvaluation studiesSeverity scoresMortality

Supplementary material

supp.pdf (24 kb)
Supplementary material (PDF 20 KB)

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Maité Garrouste-Orgeas
    • 1
  • Gilles Troché
    • 2
  • Elie Azoulay
    • 3
  • Antoine Caubel
    • 1
  • Arnaud de Lassence
    • 4
  • Christine Cheval
    • 5
  • Laurent Montesino
    • 6
  • Marie Thuong
    • 7
  • François Vincent
    • 8
  • Yves Cohen
    • 9
  • Jean-François Timsit
    • 6
    • 10
  1. 1.Service de Réanimation PolyvalenteHôpital Saint Joseph ParisFrance
  2. 2.Surgical ICUAntoine Béclère Teaching HospitalClamartFrance
  3. 3.Medical ICUSaint Louis Teaching HospitalParisFrance
  4. 4.Medical ICULouis Mourier Teaching Hospital ColombesFrance
  5. 5.Surgical Vascular ICUSaint Joseph Hospital ParisFrance
  6. 6.Medical ICUBichat Teaching HospitalParisFrance
  7. 7.Medical-Surgical ICUDelafontaine HospitalSaint DenisFrance
  8. 8.Renal-ICUTenon Teaching Hospital ParisFrance
  9. 9.Medical ICUAvicenne Teaching Hospital BobignyFrance
  10. 10.Epidemiology and Biostatistics DepartmentBichat Teaching Hospital ParisFrance