Intensive Care Medicine

, Volume 28, Issue 2, pp 170–177

Cognitive and perceived health status in patient with chronic obstructive pulmonary disease surviving acute on chronic respiratory failure: a controlled study

Authors

  • Nicolino Ambrosino
    • Pulmonary Division, Salvatore Maugeri Foundation IRCCS, Scientific Institute of Gussago, 25064 Gussago, Italy
  • Gisella Bruletti
    • Psychological Unit, Salvatore Maugeri Foundation IRCCS. Scientific Institute of Gussago, 25064 Gussago, Italy
  • Valnea Scala
    • Psychological Unit, Salvatore Maugeri Foundation IRCCS. Scientific Institute of Gussago, 25064 Gussago, Italy
  • Roberto Porta
    • Pulmonary Division, Salvatore Maugeri Foundation IRCCS, Scientific Institute of Gussago, 25064 Gussago, Italy
  • Michele Vitacca
    • Pulmonary Division, Salvatore Maugeri Foundation IRCCS, Scientific Institute of Gussago, 25064 Gussago, Italy
Original

DOI: 10.1007/s00134-001-1165-6

Cite this article as:
Ambrosino, N., Bruletti, G., Scala, V. et al. Intensive Care Med (2002) 28: 170. doi:10.1007/s00134-001-1165-6

Abstract

Objective: To evaluate the perceived health and cognitive status in survivors of chronic obstructive pulmonary disease (COPD) exacerbations requiring mechanical ventilation. Design and setting: Prospective controlled cohort study in a respiratory intermediate intensive care unit. Patients: Sixty-three COPD patients at their first episode of acute on chronic respiratory failure requiring mechanical ventilation, controls were 34 consecutive stable COPD patients on long-term oxygen therapy with no previous ICU admission. Measurements and results: Perceived health and cognitive status by means of the Nottingham Health Profile (NHP) and the Mini Mental State (MMS), respectively, at discharge and 3 and 6 months thereafter. At discharge patients showed significantly worse mean values than controls in MMS and in all NHP dimensions except pain. The MMS score was below 24, the threshold level of cognitive impairment, in 43% patients of the study group but only 3% of controls (p=0.006). Six months after discharge patients showed NHP and MMS values similar to those of controls and the proportion of patients with a MMS score below 24 had significantly decreased to 17%, a value not significantly different from that in controls (5%). Conclusions: COPD patients surviving their first episode of acute on chronic respiratory failure requiring mechanical ventilation, suffer worsen perceived health status and cognitive function, which 6 months after discharge may improve to levels similar to those in stable COPD patients on long-term oxygen therapy with no previous ICU admission.

Exacerbations Recovery Outcome Health-related quality of life

Copyright information

© Springer-Verlag 2002