Short Communication

Diabetologia

, Volume 55, Issue 1, pp 88-93

Open Access This content is freely available online to anyone, anywhere at any time.

Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study

  • F. SoriguerAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Endocrinology and Nutrition, Hospital Universitario Carlos Haya, Plaza del Hospital Civil Email author 
  • , A. GodayAffiliated withDepartment of Endocrinology and Nutrition, Hospital del Mar
  • , A. Bosch-ComasAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainInstitut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
  • , E. BordiúAffiliated withLaboratorio de Endocrinología, Hospital Universitario S. Carlos de Madrid
  • , A. Calle-PascualAffiliated withDepartment of Endocrinology and Nutrition, Hospital Universitario S. Carlos de Madrid
  • , R. CarmenaAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Medicine and Endocrinology, Hospital Clínico Universitario de Valencia
  • , R. CasamitjanaAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainBiomedic Diagnostic Centre University Hospital Clínic de Barcelona
  • , L. CastañoAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDiabetes Research Group, Hospital Universitario de Cruces, UPV-EHU
  • , C. CastellAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainPublic Health Division, Department of Health, Autonomous Government of Catalonia
    • , M. CataláAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Medicine and Endocrinology, Hospital Clínico Universitario de Valencia
    • , E. DelgadoAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Endocrinology and Nutrition, Hospital Central de Asturias
    • , J. FranchAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainEAP Raval Sud, Institut Català de la Salut, Red GEDAPS, Primary Care, Unitat de Suport a la Recerca (IDIAP–Fundació Jordi Gol)
    • , S. GaztambideAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDiabetes Research Group, Hospital Universitario de Cruces, UPV-EHU
    • , J. GirbésAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDiabetes Unit, Hospital Arnau de Vilanova
    • , R. GomisAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainInstitut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)Endocrinology and Diabetes Unit, Hospital Clínic de Barcelona, Universitat de Barcelona (UB)
    • , G. GutiérrezAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDiabetes Research Group, Hospital Universitario de Cruces, UPV-EHU
    • , A. López-AlbaAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainSpanish Diabetes Society
    • , M. T. Martínez-LarradAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainLipids and Diabetes Laboratory, Hospital Universitario S. Carlos de Madrid
    • , E. MenéndezAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Endocrinology and Nutrition, Hospital Central de Asturias
    • , I. Mora-PecesAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainEmergency Service, Hospital Nuestra Señora de los Reyes
    • , E. OrtegaAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainInstitut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)Endocrinology and Diabetes Unit, Hospital Clínic de Barcelona, Universitat de Barcelona (UB)
    • , G. Pascual-ManichAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Spain
    • , G. Rojo-MartínezAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Endocrinology and Nutrition, Hospital Universitario Carlos Haya, Plaza del Hospital Civil
    • , M. Serrano-RiosAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainLipids and Diabetes Laboratory, Hospital Universitario S. Carlos de Madrid
    • , S. ValdésAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Endocrinology and Nutrition, Hospital Universitario Carlos Haya, Plaza del Hospital Civil
    • , J. A. VázquezAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDiabetes National Plan, Ministry of Health
    • , J. VendrellAffiliated withCentro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), SpainDepartment of Endocrinology and Nutrition, Hospital Universitario Joan XXIII, Institut d’Investigacions Sanitaries Pere Virgili

Abstract

Aims/hypothesis

The Di@bet.es Study is the first national study in Spain to examine the prevalence of diabetes and impaired glucose regulation.

Methods

A population-based, cross-sectional, cluster sampling study was carried out, with target population being the entire Spanish population. Five thousand and seventy-two participants in 100 clusters (health centres or the equivalent in each region) were randomly selected with a probability proportional to population size. Participation rate was 55.8%. Study variables were a clinical and demographic structured survey, lifestyle survey, physical examination (weight, height, BMI, waist and hip circumference, blood pressure) and OGTT (75 g).

Results

Almost 30% of the study population had some carbohydrate disturbance. The overall prevalence of diabetes mellitus adjusted for age and sex was 13.8% (95% CI 12.8, 14.7%), of which about half had unknown diabetes: 6.0% (95% CI 5.4, 6.7%). The age- and sex-adjusted prevalence rates of isolated impaired fasting glucose (IFG), isolated impaired glucose tolerance (IGT) and combined IFG–IGT were 3.4% (95% CI 2.9, 4.0%), 9.2% (95% CI 8.2, 10.2%) and 2.2% (95% CI 1.7, 2.7%), respectively. The prevalence of diabetes and impaired glucose regulation increased significantly with age (p < 0.0001), and was higher in men than in women (p < 0.001).

Conclusions/interpretation

The Di@bet.es Study shows, for the first time, the prevalence rates of diabetes and impaired glucose regulation in a representative sample of the Spanish population.

Keywords

Epidemiology Prevalence Spain Type 2 diabetes mellitus