Cellular and Molecular Life Sciences CMLS

, Volume 55, Issue 2, pp 271–283

Structure, function and evolution of antifreeze proteins

Article

DOI: 10.1007/s000180050289

Cite this article as:
Ewart, K., Lin, Q. & Hew, C. CMLS, Cell. Mol. Life Sci. (1999) 55: 271. doi:10.1007/s000180050289

Abstract

Antifreeze proteins bind to ice crystals and modify their growth. These proteins show great diversity in structure, and they have been found in a variety of organisms. The ice-binding mechanisms of antifreeze proteins are not completely understood. Recent findings on the evolution of antifreeze proteins and on their structures and mechanisms of action have provided new understanding of these proteins in different contexts. The purpose of this review is to present the developments in contrasting research areas and unite them in order to gain further insight into the structure and function of the antifreeze proteins.

Key words. Antifreeze; ice; protein structure; protein function; evolution; cell membranes. 

Copyright information

© Birkhäuser Verlag, Basel 1999

Authors and Affiliations

  1. 1.NRC Institute for Marine BiosciencesHalifaxCanada
  2. 2.Research Institute, Hospital for Sick Children and Departments of Clinical Biochemistry and BiochemistryUniversity of TorontoTorontoCanada

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