Cellular and Molecular Life Sciences

, Volume 67, Issue 24, pp 4135–4169

Crustacean neuropeptides

  • Andrew E. Christie
  • Elizabeth A. Stemmler
  • Patsy S. Dickinson

DOI: 10.1007/s00018-010-0482-8

Cite this article as:
Christie, A.E., Stemmler, E.A. & Dickinson, P.S. Cell. Mol. Life Sci. (2010) 67: 4135. doi:10.1007/s00018-010-0482-8


Crustaceans have long been used for peptide research. For example, the process of neurosecretion was first formally demonstrated in the crustacean X-organ–sinus gland system, and the first fully characterized invertebrate neuropeptide was from a shrimp. Moreover, the crustacean stomatogastric and cardiac nervous systems have long served as models for understanding the general principles governing neural circuit functioning, including modulation by peptides. Here, we review the basic biology of crustacean neuropeptides, discuss methodologies currently driving their discovery, provide an overview of the known families, and summarize recent data on their control of physiology and behavior.


TranscriptomicsMass spectrometryPeptidergic neuromodulationNeurotransmitterNeurohormonePeptidomicsStomatogastric ganglionCardiac ganglion

Copyright information

© Springer Basel AG 2010

Authors and Affiliations

  • Andrew E. Christie
    • 1
  • Elizabeth A. Stemmler
    • 2
  • Patsy S. Dickinson
    • 3
  1. 1.Program in Neuroscience, John W. and Jean C. Boylan Center for Cellular and Molecular PhysiologyMount Desert Island Biological LaboratorySalisbury CoveUSA
  2. 2.Department of ChemistryBowdoin CollegeBrunswickUSA
  3. 3.Department of BiologyBowdoin CollegeBrunswickUSA