Cellular and Molecular Life Sciences

, 65:41

Molecular and Cellular Basis of Regeneration and Tissue Repair

On dorsal/ventral-specific genes in the iris during lens regeneration
Multi-author Review

DOI: 10.1007/s00018-007-7429-8

Cite this article as:
Tsonis, P.A. & Makarev, E. Cell. Mol. Life Sci. (2008) 65: 41. doi:10.1007/s00018-007-7429-8


Recent experiments on gene expression during lens regeneration in adult newts have revealed that both the regeneration-competent dorsal iris and the regeneration-incompetent ventral iris are quite active in expressing important regulatory genes. In this paper we outline some of the issues pertaining to this dorsal/ventral specificity and identity. (Part of a Multi-author Review)


Newtregenerationdorsal/ventral irisbone morphogenetic proteins (BMPs)

Copyright information

© Birkhaueser 2007

Authors and Affiliations

  1. 1.Laboratory of Molecular Biology, Department of Biology and Center for Tissue Regeneration and EngineeringUniversity of DaytonDaytonUSA