Cellular and Molecular Life Sciences CMLS

, Volume 63, Issue 24, pp 2881–2885

Antiquitin, a relatively unexplored member in the superfamily of aldehyde dehydrogenases with diversified physiological functions

Authors

    • Department of BiochemistryThe Chinese University of Hong Kong, Shatin, N. T.
  • C. H. K. Cheng
    • Department of BiochemistryThe Chinese University of Hong Kong, Shatin, N. T.
  • W. -K. Tang
    • Department of BiochemistryThe Chinese University of Hong Kong, Shatin, N. T.
Visions & Reflections (Minireview)

DOI: 10.1007/s00018-006-6089-4

Cite this article as:
Fong, W.-., Cheng, C.H.K. & Tang, W.-. Cell. Mol. Life Sci. (2006) 63: 2881. doi:10.1007/s00018-006-6089-4

Abstract.

Antiquitin is a member of the aldehyde dehydrogenase superfamily. Sequence analyses indicate that the protein is highly conserved from plants to animals. The plant antiquitins are generally believed to play a role in osmoregulation and/or detoxification. The physiological functions of animal antiquitins remain largely elusive, their involvement in a number of human diseases has been implicated.

Keywords.

Antiquitinaldehyde dehydrogenasedetoxificationosmoregulationalpha-aminoadipic semialdehyde

Copyright information

© Birkhäuser Verlag, Basel 2006