, Volume 59, Issue 6, pp 421-429

Islet Transplantation: Factors in Short-Term Islet Survival

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Abstract

Islet transplantation has the potential to cure type 1 diabetes. In recent years, the proportion of patients achieving initial insulin independence has improved, but longer term outcomes remain poor compared to those for whole pancreas transplants. This review article will discuss factors affecting islet yield and viability leading up to transplantation and in the immediate post-transplant period.