European Journal of Pediatrics

, Volume 159, Issue 1, pp 91–94

Presence of metabolic cardiovascular syndrome in obese children

  • Györgyi Csábi
  • Katalin Török
  • Sára Jeges
  • Dénes Molnár
ORIGINAL PAPER

DOI: 10.1007/PL00013812

Cite this article as:
Csábi, G., Török, K., Jeges, S. et al. Eur J Pediatr (2000) 159: 91. doi:10.1007/PL00013812

Abstract

The aim of the present study was to investigate the aggregation of cardiovascular risk factors (hyperinsulinaemia, impaired glucose tolerance, dyslipidaemia, and hypertension) in 180 (77 female, 103 male) obese and 239 control children. Blood glucose, serum insulin and lipid levels were determined from blood samples taken after an overnight fast. Oral glucose tolerance tests were performed and blood glucose concentrations were monitored. The body mass index, body fat (on the basis of skinfold measurements), lean body mass and waist/hip ratio were calculated and blood pressure was measured five times in all subjects. It was shown that only 14.4% of obese children were free from any risk factors, in contrast to 79.1% of the control children. Four risk factors (metabolic cardiovascular syndrome) were found in 8.9% of the obese children (8.7% in males and 9.l % in females) while none could be detected in controls. Considerable differences were also detected in the prevalence of one, two or three risk factors between control and obese children. Patients with the metabolic cardiovascular syndrome could not be characterized by any of the investigated anthropometric characteristics, but the duration of obesity was significantly longer in these children.

Conclusion Potential risk factors for cardiovascular diseases already tend to cluster in childhood and they are strongly associated with obesity. Our observations suggest that the development of the metabolic cardiovascular syndrome has its origin in childhood.

Key words Childhood obesity Hypertension Hyperinsulinaemia Metabolic cardiovascular syndrome Cardiovascular risk factors 

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Györgyi Csábi
    • 1
  • Katalin Török
    • 1
  • Sára Jeges
    • 2
  • Dénes Molnár
    • 1
  1. 1.Department of Paediatrics University Medical School of Pécs, József Attila u.7, 7623 Pécs, Hungary Tel.: +36-72-310144, Fax: 36-72-314937HU
  2. 2.Central Research Laboratory, University Medical School of Pécs, József Attila u.7, 7623 Pécs, HungaryHU