World Journal of Surgery

, Volume 23, Issue 5, pp 446–451

Regeneration of Abdominal Wall Aponeurosis: New Dimension in Marlex Peritoneal Sandwich Repair of Incisional Hernia

  • B.G. Matapurkar
  • A. Bhargave
  • Leelawathi Dawson
  • B. Sonal

DOI: 10.1007/PL00012326

Cite this article as:
Matapurkar, B., Bhargave, A., Dawson, L. et al. World J. Surg. (1999) 23: 446. doi:10.1007/PL00012326


Loss of abdominal wall substance is a major cause of incisional hernia formation. It makes repair of this iatrogenic human ailment a difficult surgical problem. The abdominal wall substance loss has compelled the world's surgical community dealing with this condition to substantiate the repair with extra material such as skin, fascia, wire mesh, and lately biocompatible synthetic mesh. Even though the synthetic mesh is compatible and well tolerated by body tissues, it is not without complications. Regenerative repair in the region of the abdominal wall with substance loss is probably the best repair if it can be achieved. With reasonable success in animal experiments and the positive regenerative capacity of stem cells to transform the peritoneum into an aponeurotic layer, the new technique using a Marlex peritoneal sandwich for repair of large incisional hernias was attempted but was not reported in the article published in the World Journal of Surgery in 1991. The present study is based on experiments on seven mongrel dogs. A suitable embryonal segment of autogenous peritoneum was excised and transfered to the rectus sheath region. The gross appearance of the grafted membrane 3 months after operation revealed tough, thick tissue formation. The histology confirmed the presence of collagen fiber tissue in layers similar to the aponeurosis in the grafted peritoneal membrane. The use of this regeneration in the Marlex peritoneal sandwich technique of repair of large incisional hernias and the scientific rationale of tissue regeneration by desired metaplasia is discussed.

Copyright information

© 1999 by the Société Internationale de Chir ugie

Authors and Affiliations

  • B.G. Matapurkar
    • 1
  • A. Bhargave
    • 2
  • Leelawathi Dawson
    • 3
  • B. Sonal
    • 4
  1. 1.Department of Surgery, Lok Nayak Hospital and Maulana Azad Medical College, New Delhi 110002, IndiaIN
  2. 2.Academic Section, Safdarjung Hospital Complex, New Delhi 110029, IndiaIN
  3. 3.Institute of Pathology, Indian Council of Medical Research, Safdarjung Hospital Complex, New Delhi 110029, IndiaIN
  4. 4.Indian Council of Medical Research, Maulana Azad Medical College, New Delhi 110002, IndiaIN
  5. 5.Department of Surgery, Maulana Azad Medical College, New Delhi 110002, IndiaIN