European Journal of Clinical Microbiology and Infectious Diseases

, Volume 20, Issue 5, pp 354–357

Evidence of Increased Risk for Leishmania infantum Infection Among HIV-Seronegative Intravenous Drug Users from Southern Spain

  • J. A. Pineda
  • J. Macías
  • F. Morillas
  • J. Fernández-Ochoa
  • J. Cara
  • R. de la Rosa
  • J. A. Mira
  • J. Martín-Sánchez
  • M. González
  • J. Delgado
  • C. Acedo
  • E. Lissen
Note

DOI: 10.1007/PL00011276

Cite this article as:
Pineda, J., Macías, J., Morillas, F. et al. EJCMID (2001) 20: 354. doi:10.1007/PL00011276

Abstract

 To assess the prevalence of markers of Leishmania infection, 93 intravenous drug users and 77 non-users of intravenous drugs underwent a Leishmania skin test and a serum Leishmania antibody search. All participants were human immunodeficiency virus seronegative. The Leishmania skin test was positive in 24 intravenous drug users and in 10 non-users of intravenous drugs (P=0.038). Leishmania seropositivity was detected in 3 of 11 active intravenous drug users and in 3 of 82 former drug injectors (P=0.02). Positivity in the Leishmania skin test was associated with intravenous drug use (adjusted odds ratio, 2.33; 95% confidence interval, 1.03–5.24). The prevalence of Leishmania infection markers among intravenous drug users is higher than that among controls. This suggests that this parasite spreads through the sharing of needles.

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • J. A. Pineda
    • 1
  • J. Macías
    • 1
  • F. Morillas
    • 2
  • J. Fernández-Ochoa
    • 3
  • J. Cara
    • 4
  • R. de la Rosa
    • 5
  • J. A. Mira
    • 1
  • J. Martín-Sánchez
    • 2
  • M. González
    • 6
  • J. Delgado
    • 5
  • C. Acedo
    • 2
  • E. Lissen
    • 5
  1. 1.Servicio de Medicina Interna, Hospital Universitario Virgen de Valme, Carretera de Cádiz s/n, 41014 Seville, Spain e-mail: japineda@nacom.es Tel.: +34-5-5015777 Fax: +34-5-5012390ES
  2. 2.Departamento de Parasitología, Facultad de Farmacia, Universidad de Granada, Campus Cartuja s/n, 18071 Granada, SpainES
  3. 3.Unidad de Desintoxicación Hospitalaria, Hospital el Tomillar, Carretera Alcalá–Dos Hermanas Km 6, 41700 Dos Hermanas, Seville, SpainES
  4. 4.Servicios Médicos, Centro Penitenciario de Sevilla, Carretera Torreblanca–Mairena del Alcor Km 3.5, 41007 Seville, SpainES
  5. 5.Viral Hepatitis and AIDS Study Group, Departamento de Medicina Interna, Hospital Universitario Virgen del Rocío, Avenida Manuel Siurot s/n, 41013 Seville, SpainES
  6. 6.Unidad de Desintoxicación Hospitalaria, Hospital Victoria Eugenia, Avenida de la Cruz Roja 1, 41009 Seville, SpainES