Clinical Rheumatology

, Volume 20, Issue 2, pp 123–127

Total Mortality is Increased in Rheumatoid Arthritis. A 17-Year Prospective Study

Authors

  • T. Riise
    • Institute of Clinical Medicine, University of Tromsø
  • B. K. Jacobsen
    • Institute of Community Medicine, University of Tromsø
  • J. T. Gran
    • Institute of Clinical Medicine, University of Tromsø
  • H.-J. Haga
    • Department of Rheumatology, University Hospital of Bergen, Norway
  • E. Arnesen
    • Institute of Community Medicine, University of Tromsø
Original Article

DOI: 10.1007/PL00011191

Cite this article as:
Riise, T., Jacobsen, B., Gran, J. et al. Clin Rheumatol (2001) 20: 123. doi:10.1007/PL00011191

Abstract:

The purpose of this study was to determine the total and cause-specific mortality in rheumatoid arthritis (RA) patients compared to a control population in northern Norway. One hundred and eighty-seven patients with RA and 930 population controls matched for age, gender and municipality were followed until death or for a maximum of 17 years. The total mortality in RA patients was twice that of their controls (MRR = 2.0, 95% CI = 1.6-2.5). Patients possessing serum rheumatoid factors did not have a higher relative mortality than the seronegative patients. There was no statistically significant increased mortality from cancer or cardiovascular diseases. Indications for a higher death rate in RA patients than in controls were found for infection and sudden death.

Key words:Cancer – Infection – Mortality – Rheumatoid arthritis – Sudden death

Copyright information

© Clinical Rheumatology 2001