Journal of Hepato-Biliary-Pancreatic Surgery

, Volume 5, Issue 1, pp 41–47

Surgical management of intrahepatic cholangiocarcinoma: A 31-year experience

  • Mark J. Lieser
  • M. Kevin Barry
  • Charles Rowland
  • Duane M. Ilstrup
  • David M. Nagorney

DOI: 10.1007/PL00009949

Cite this article as:
Lieser, M., Barry, M., Rowland, C. et al. J Hep Bil Pancr Surg (1998) 5: 41. doi:10.1007/PL00009949

Abstract:

Intrahepatic cholangiocarcinoma (ICC) is the second most common malignant primary tumor of the liver. It is, though, a rare tumor and little is known regarding its natural history, clinicopathologic characteristics, or the outcomes of surgical therapy. We reviewed the experience of 61 patients with ICC seen by the surgical service at the Mayo Clinic over a 31-year period. Patient demographic and clinical data were recorded, as were survival statistics. Pathologic data were also obtained and patients stratified according to the TNM classification. Twenty-eight patients were resected for cure. Overall, 45 patients died of ICC. Of the patients resected for cure, survival at 3 years was 60%. No pathologic condition was found to be associated with the development of ICC. Overall survival correlated with stage of the tumor. Among patients resected for cure, stage did not correlate with survival. Prognosis for patients with ICC remains poor; resection, though, appears to prolong survival.

Key words: intrahepatic cholangiocarcinomacholangiocarcinomaliverhepatic resection

Copyright information

© Springer-Verlag Tokyo 1998

Authors and Affiliations

  • Mark J. Lieser
    • 1
  • M. Kevin Barry
    • 2
  • Charles Rowland
    • 2
  • Duane M. Ilstrup
    • 2
  • David M. Nagorney
    • 1
  1. 1.Departments of General and Gastroenterologic Surgery and
  2. 2.Biostatistics, Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USAUS