Journal of Molecular Evolution

, Volume 44 , Issue 4 , pp 378 –382

Sequences and Evolution of Human and Squirrel Monkey Blue Opsin Genes

Authors

  • Lawrence C.  Shimmin
    • Human Genetics Center, SPH, University of Texas Houston Health Science Center, P.O. Box 20334, Houston, TX 77225, USA
  • Phuong  Mai
    • Human Genetics Center, SPH, University of Texas Houston Health Science Center, P.O. Box 20334, Houston, TX 77225, USA
  • Wen-Hsiung  Li
    • Human Genetics Center, SPH, University of Texas Houston Health Science Center, P.O. Box 20334, Houston, TX 77225, USA

DOI: 10.1007/PL00006157

Cite this article as:
Shimmin, L., Mai, P. & Li, W. J Mol Evol (1997) 44: 378. doi:10.1007/PL00006157

Abstract.

The sequences of the entire blue opsin gene in the squirrel monkey (Saimiri boliviensis) and the five introns of the human blue opsin gene were obtained. Intron 3 of these genes contains an Alu sequence and intron 4 contains a partial mer13 sequence. A comparison of the squirrel monkey opsin sequence with published mammalian opsin sequences shows that features believed to be functionally critical are all conserved. However, the blue opsin has evolved twice as fast as rhodopsin and is only as conservative as the β globin, which has evolved at the average rate of mammalian proteins. Interestingly, the interhelical loops are, on average, actually more conservative than the transmembrane α helical regions. The introns of the blue opsin gene have evolved at the average rate of introns in primate genes.

Key words: Blue opsin — Amino acid conservation — Visual opsin — Repetitive elements

Copyright information

© Springer-Verlag New York Inc. 1997