Gold nanoparticles designed for combining dual modality imaging and radiotherapy Scientific Papers DOI:
Cite this article as: Alric, C., Serduc, R., Mandon, C. et al. Gold Bull (2008) 41: 90. doi:10.1007/BF03216586 About the authors Christophe Alric obtained his Master degree in inorganic chemistry at the University of Lyon (France) and he is now a PhD student in the group of Prof. Olivier Tillement. His research activities are focused on the elaboration of gold nanoparticles combining medical imaging and therapeutic capacities. Céline A. Mandon received the Doctorat de spécialité in Biochemistry (2005) from the Université Lyon 1. She was post-doctoral researcher (2005-2006) at the Laboratory of Oxidative Stress, Chaperons and Apoptosis in Lyon (CGMC—CNRS-UMR5534), where she developed bioluminescent and fluorescent stress inducible cell based assays. She is currently post-doc researcher at the laboratory Creatis-LRMN (CNRSUMR-5220), on the Animage platform, where she is in charge of cell labeling by hybrid nanoparticles, used as contrast agents for in vivo imaging. Jacqueline Taleb received a diploma in pharmacy (1998) from the University of Algiers and a Master 2 Research in Biomedical engineering (2007) from the Université Lyon 1. The subject of the training was “X-ray radiosensibilizating effects of gold nanoparticules on healthy and tumoral cells”. She is currently PhD student at Creatis-LRMN (CNRS-UMR-5220), on the Animage platform, where she is developing a tumoral model and testing radiotherapeutic effects of radioactive nanoparticules and their detection by MR, optic and scientigraphic imaging.
Dr. Géraldine Le Duc obtained her PhD at the interface between biology and physics in 1996. After a one year position in US, she was hired at the ESRF, in order to develop preclinical activities. She is responsible for the BioMedical Facility group providing support and expertise in cellular biology, molecular biology and in vivo experimentation. She is deeply involved in the ESRF preclinical imaging and radiotherapy program, supervising PhD students and postdoctoral scientists and holding collaborations.
Alice A. Le Meur — Herland received a professional master “imagerie de la santé” (2006) from the Université de Caen Basse-Normandie. She did her training period at CYCERON (UMR-CNRS 6185, Caen) where she studied the migration of mesenchymal stem cells at the cerebral level, using a contrast agent, allowing a follow-up by MRI. She is currently engineer on the platform ANIMAGE (Université Claude Bernard Lyon1, CREATIS-LRMN) where she is in charge of in vivo imaging. Claire Billotey (MD, PhD) is specialized in Medical Biology and Nuclear Medicine. Her professional activities are shared between her medical senior activity in the department of nuclear medicine of the hospital Edouard Herriot (Lyon, France) and her research activities in the University of Lyon 1. Her research interests are focused on the biological evaluation and validation of hybrid nanoparticles designed for biological and medical applications in the field of diagnosis by imaging and therapy. Pascal Perriat 44 years old, is professor at INSA de Lyon and belongs to the laboratory MATEIS (Materials; Science and Engineering). He develops research upon nanoparticles for biology and medicine and is specialized in soft-chemistry routes and characterization at the nanometer scale by Transmission Electron Microscopy. He is the co-author of more than 70 papers and of 5 patents.
and electrochemistry from the University of Franche-Comté (France) and completed a PhD degree in Chemistry (conducting hybrid materials) at the same institution in 2000. Afterwards, he moved to the Catholic University of Louvain-la-Neuve (Belgium) for studying the radical polymerization initiated from a solid surface. Since 2002 he is assistant professor at the University Claude Bernard of Lyon (France). His main research activities are focused on the development of nanoparticles combining several imaging techniques and therapy.
Olivier Tillement studied at the Ecole Normale Supérieure (Paris, France) and obtained his PhD in Chemistry at the university Pierre et Marie Curie in 1992. After a one year position at Tufts University (Boston, USA), he was recruited in 1993 as assistant professor. Olivier Tillement is Professor of Chemistry at the University of Lyon since 2000. The research work of his group includes the synthesis of single crystal fibers for optical applications and of multifunctional nanoparticles for biomedical applications.