Case Report

Annals of Nuclear Medicine

, Volume 11, Issue 4, pp 335-338

Discordant splenic uptake of Tc-99m colloid and Tc-99m denatured RBC in candidiasis-endocrinopathy syndrome

  • Tamio AburanoAffiliated withDepartment of Radiology, Asahikawa Medical College
  • , Ryuji KatadaAffiliated withDepartment of Radiology, Asahikawa Medical College
  • , Noriyuki ShukeAffiliated withDepartment of Radiology, Asahikawa Medical College
  • , Wakako YamamotoAffiliated withDepartment of Radiology, Asahikawa Medical College
  • , Takako KawakamiAffiliated withSecond Department of Internal Medicine, Asahikawa Medical College Hospital
  • , Isao MakinoAffiliated withSecond Department of Internal Medicine, Asahikawa Medical College Hospital
  • , Junichi SatoAffiliated withRadiological Service, Asahikawa Medical College Hospital
  • , Yukio IshikawaAffiliated withRadiological Service, Asahikawa Medical College Hospital

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Abstract

We report discordant splenic uptake of Tc-99m colloid and Tc-99m heat-denatured red blood cells (RBC) which occurred in a 21-year-old female with candidiasis-endocrinopathy syndrome. Tc-99m colloid liver-spleen imaging showed no splenic uptake, suggesting the presence of functional asplenia. A subsequent Tc-99m heat-denatured RBC study clearly revealed a small spleen with preserved sequestrating function. These results may demonstrate that the qualitative dissociation of splenic functions in processing colloid and denatured RBC in functional asplenia: the sequestration function remains while the reticuloendothelial system is impaired.

Key words

Tc-99m colloid Tc-99m denatured RBC imaging functional asplenia candidiasis-endocrinopathy syndrome